Results 101 to 110 of about 195,947 (391)

Macroscopic Anisotropic Bone Material Properties in Children with Severe \u3cem\u3eOsteogenesis imperfecta\u3c/em\u3e [PDF]

, 2017
Children with severe osteogenesis imperfecta(OI) typically experience numerous fractures and progressive skeletal deformities over their lifetime. Recent studies proposed finite element models to assess fracture risk and guide clinicians in determining ...
Albert, Carolyne, Harris, Gerald, Jameson, John, Smith, Peter, Tarima, Sergey   +4 more
core   +1 more source

Helical mutations in type I collagen that affect the processing of the amino-propeptide result in an Osteogenesis Imperfecta/Ehlers-Danlos Syndrome overlap syndrome [PDF]

, 2013
Background: Whereas mutations affecting the helical domain of type I procollagen classically cause Osteogenesis Imperfecta (OI), helical mutations near the amino (N)-proteinase cleavage site have been suggested to result in a mixed OI/Ehlers-Danlos ...
De Paepe, Anne, Goemans, Nathalie, Gyftodimou, Yolanda, Holmberg, Eva, Lopez-Gonzalez, Vanesa, Malfait, Fransiska, Mortier, Geert, Nampoothiri, Sheela, Petersen, Michael Bjorn, Symoens, Sofie   +9 more
core   +2 more sources

Exosomes Secreted by Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Repair Critical-Sized Bone Defects through Enhanced Angiogenesis and Osteogenesis in Osteoporotic Rats

International Journal on Biological Sciences, 2016
Bone defects caused by trauma, severe infection, tumor resection and skeletal abnormalities are common osteoporotic conditions and major challenges in orthopedic surgery, and there is still no effective solution to this problem.
Xin Qi, Jieyuan Zhang, H. Yuan, Zhengliang Xu, Qing Li, X. Niu, Bin Hu, Yang Wang, Xiaolin Li   +8 more
semanticscholar   +1 more source

Temporal evolution of mechanical properties of skeletal tissue regeneration in rabbits. An experimental study [PDF]

Medical & biological engineering & computing 45, 10 (2007) 989-995, 2007
Various mathematical models represent the effects of local mechanical environment on the regulation of skeletal regeneration. Their relevance relies on an accurate description of the evolving mechanical properties of the regenerating tissue. The object of this study was to develop an experimental model which made it possible to characterize the ...
arxiv  

Graded Hydroxyapatite Triply Periodic Minimal Surface Structures for Bone Tissue Engineering Applications

Advanced Healthcare Materials, EarlyView.
This study investigates the role of triply periodic minimal structures in load bearing bone tissue engineering applications. Research uses a combination of mechanical testing, material characterization, and in vitro tests to study the impact of TPMS lattice structures (gyroid, lidinoid and split‐P).
Tejas M. Koushik, Catherine M. Miller, Elsa Antunes   +2 more
wiley   +1 more source

circAKT3 positively regulates osteogenic differentiation of human dental pulp stromal cells via miR-206/CX43 axis

Stem Cell Research & Therapy, 2020
Background Human dental pulp stromal cells (hDPSCs) are promising sources of mesenchymal stem cells (MSCs) for bone tissue regeneration. Circular RNAs (circRNAs) have been demonstrated to play critical roles in stem cell osteogenic differentiation ...
Bo Zhang, Sibei Huo, Xiao Cen, Xuefeng Pan, Xinqi Huang, Zhihe Zhao   +5 more
doaj   +1 more source

The role of the membrane of the maxillary sinus in space osteogenesis under the sinus floor after elevation of the sinus floor

口腔疾病防治, 2020
With the continuous development of maxillary sinus floor elevation technology, the osteogenesis mechanism of maxillary sinus floor elevation has always been a concern of scholars.
CHEN Songling, ZHU Shuangxi
doaj   +1 more source

In situ activation of flexible magnetoelectric membrane enhances bone defect repair

Nature Communications, 2023
For bone defect repair under co-morbidity conditions, the use of biomaterials that can be non-invasively regulated is highly desirable to avoid further complications and to promote osteogenesis.
Wenwen Liu, Han Zhao, Chenguang Zhang, Shiqi Xu, Fengyi Zhang, Ling Wei, Fangyu Zhu, Ying Chen, Yumin Chen, Ying Huang, Mingming Xu, Ying He, Boon Chin Heng, Jinxing Zhang, Yang Shen, Xuehui Zhang, Houbing Huang, Lili Chen, Xuliang Deng   +18 more
doaj   +1 more source

BMP9 signaling in stem cell differentiation and osteogenesis.

American Journal of Stem Cells, 2018
Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily and play a critical role in skeletal development, bone formation and stem cell differentiation.
Joseph D. Lamplot, J. Qin, G. Nan, Jinhua Wang, Xing Liu, L. Yin, J. Tomal, Rui-dong Li, W. Shui, Hongyu Zhang, Stephanie H Kim, Wenwen Zhang, Jiye Zhang, Y. Kong, S. Denduluri, M. R. Rogers, Abdullah Pratt, R. Haydon, H. Luu, J. Angeles, Lewis L. Shi, T. He   +21 more
semanticscholar   +1 more source

Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee, Peter Lialios, Micaila Curtis, James Williams IV, Yoontae Kim, Paul Salipante, Steven Hudson, Mandy B. Esch, Moshe Levi, Joanna Kitlinska, Stella Alimperti   +10 more
wiley   +1 more source