Results 101 to 110 of about 145,083 (306)
Advanced Science, EarlyView.The senescence of macrophages leads to a decrease in the expression of Sirtuin3 (Sirt3), which in turn aggravates the NLRP3 inflammasome activation and IL‐1β secretion, thereby promoting the aging‐related osteoporosis. Sirt3‐enriched apoptotic bodies (ABs‐Sirt3) generated through genetic editing approaches can alleviate skeletal aging by targeting ...
Yanglin Wu +7 more
wiley +1 more source
\u3cem\u3eIn vitro\u3c/em\u3e Effect of Graphene Structures as an Osteoinductive Factor in Bone Tissue Engineering: A Systematic Review [PDF]
, 2018 Graphene and its derivatives have been well‐known as influential factors in differentiating stem/progenitor cells toward the osteoblastic lineage. However, there have been many controversies in the literature regarding the parameters effect on bone ...
Golzar, Hossein +7 more
core +1 more source
Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration
Advanced Science, EarlyView.Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman +5 more
wiley +1 more source
FasL induces expression of Mmp13 and Osterix in bone cells
Bone Reports, 2021 Adéla Kratochvílová +4 more
doaj +1 more source
Phytochemical Assessment on N-hexane Extract and Fractions of Marsilea Crenata Presl. Leaves Through Gc-ms [PDF]
, 2016 Estrogen deficiency causes various health problems in postmenopausal women, including osteoporosis. Phytoestrogen emerged as a potential alternative of estrogen with minimum side effects.
Agil, M. (Mangestuti) +2 more
core +4 more sources
A BioLiving Periosteum Evokes Centripetal Regeneration in Challenging Bone Defects
Advanced Science, EarlyView.Large bone defects often suffer from insufficient central healing. This study engineers a BioLiving periosteum that mimics the native structure. It sequentially delivers remote chemical cues and contact physical cues in a signaling‐relay manner, effectively recruiting and guiding endogenous cells toward the defect center.
Yang Shi +12 more
wiley +1 more source
Spatial Distribution of Macrophages During Callus Formation and Maturation Reveals Close Crosstalk Between Macrophages and Newly Forming Vessels [PDF]
, 2019 Macrophages are essential players in the process of fracture healing, acting by remodeling of the extracellular matrix and enabling vascularization. Whilst activated macrophages of M1-like phenotype are present in the initial pro-inflammatory phase of ...
Aulich, Linus +11 more
core +1 more source
Advanced Science, EarlyView.The versatile CaO2@CuMOF@HAP nanohybrid demonstrates an outstanding MMP9/pH‐triggered release performance for sequential release of osteogenic growth peptide into deep‐seated tumor‐infiltrated bone destruction areas and dual ions into tumor cells, enabling efficient tumor‐associated osteolysis restoration and tumor elimination for more comprehensive ...
Lan Liu +8 more
wiley +1 more source
Analysis of cell cycle related gene expression in Myb deficient mandible – a pilot study
Bone Reports, 2021 Sabina Stouracova +5 more
doaj +1 more source