Results 201 to 210 of about 210,118 (389)

Dual‐Anchored Clickable Peptide via SPAAC for Gelatinase‐Responsive Antibacterial and Osteogenic Functions on Titanium Implants

Advanced Science, EarlyView.
To address the infection‐associated orthopedic implant failures, this study presents a gelatinase‐responsive antibacterial titanium implant (Ti‐Dual) featuring a dual‐anchored fusion peptide containing antibacterial (HHC36) and osteogenic (RGD) domains connected by a cleavable GPLGV linker.
Ru Zhong, Hang Zhou, Chenyang Ye, Lei Chu, Lin Wang, Yingjun Wang   +5 more
wiley   +1 more source

Low-dose IL-34 has no effect on osteoclastogenesis but promotes osteogenesis of hBMSCs partly via activation of the PI3K/AKT and ERK signaling pathways [PDF]

, 2021
Jianxiang Xu, Lifeng Fu, Jinwu Bai, Huiming Zhong, Zhihui Kuang, Chengwei Zhou, Bin Hu, Licheng Ni, Ying Li, Erman Chen, Wei Zhang, Jiaqi Wu, Deting Xue, Weixu Li, Zhijun Pan   +14 more
openalex   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Mechanical Strain‐Programmed SDC1+ Sheath Fibroblasts Trigger CXCR4hi Neutrophil‐Mediated Enthesitis in Ankylosing Spondylitis

Advanced Science, EarlyView.
In ankylosing spondylitis (AS), mechanical strain‐programmed SDC1+ sheath fibroblasts secrete CXCL5 to recruit neutrophils and promote the activation of CXCR4hi neutrophils, thereby exacerbating enthesitis by promoting neutrophil extracellular traps (NETs) formation. SOX5 controls the generation of SDC1+ sheath fibroblasts via super‐enhancers.
Jiajie Lin, Zepeng Su, Yipeng Zeng, Yi Zhou, Chenying Zeng, Weihao Zhang, Qibo Li, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Guan Zheng, Wenhui Yu, Zhongyu Xie   +13 more
wiley   +1 more source

Distraction Osteogenesis Reconstruction Following Resection of Bone Sarcomas [PDF]

Anthony Bozzo, Varun Aysola, Caleb M. Yeung, John H. Healey, Daniel E. Prince   +4 more
openalex   +1 more source

Ten years follow up after prenatal transplantation of fetal mesenchymal stem cell in a patient with severe osteogenesis imperfecta [PDF]

, 2013
Cecilia Götherström, Blanc Katarina Le, Eva AEstrom, Jahan Taslimi, Gail E. Graham, Uwe Ewald, Magnus Westgren   +6 more
openalex   +1 more source

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

PEG-rHuMGDF Causes Osteogenesis by Stimulating Osteoblast Differentiation and Inhibiting Osteoclast Differentiation in Normal Mice.

, 2001
Youichi Ide, Eri Yamanaka, Yasuko Namiki, Yasuko Kikuchi, Hiromi Ishii, Jun‐ichi Kawahara, Kunio Doi   +6 more
openalex   +2 more sources

Remodeling Periodontitis Microenvironment for Osteogenesis by Using a Reactive Oxygen Species-Cleavable Nanoplatform

, 2021
Xinyi Qiu, Yijun Yu, Hanxiao Liu, Xincong Li, Weibin Sun, Wenlei Wu, Chao Liu, Leiying Miao   +7 more
openalex   +1 more source

Osteogenesis Imperfecta [PDF]

Proceedings of the Royal Society of Medicine, 1916
openaire   +2 more sources