Results 221 to 230 of about 145,083 (306)

MicroRNA-127-3p Inhibits In Vitro Osteogenesis and Dampens Trauma-Induced Heterotopic Ossification In Vivo. [PDF]

J Orthop Res
Brito VGB, Bell-Hensley A, Zheng H, Liu J, Narayan A, Oliveria SHP, Pan H, McAlinden A.   +7 more
europepmc   +1 more source

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo, Roni Zemet, Allyson Nevins, Katherine Abraham, April D. Adams   +4 more
wiley   +1 more source

Current Trends and Future Prospects of Integrating Electrospinning With 3D Printing Techniques for Mimicking Bone Extracellular Matrix Scaffolds

Journal of Polymer Science, Volume 63, Issue 6, Page 1481-1504, 15 March 2025.
ABSTRACT This article presents a review of the recent findings on the combination of electrospun nanofibers and three‐dimensional (3D)‐printed structures for extracellular matrix (ECM) scaffolds for bone tissue engineering. We explore the synergy between electrospinning (ES), which produces highly porous, fibrous structures from materials like collagen
Kardo Khalid Abdullah, Kolos Molnár
wiley   +1 more source

Advanced multifunctional thermo- and electro-stimulative hydrogels for bone regeneration. [PDF]

Mater Today Bio
Zhang Y, Wang Y, Zou J, Huang J, Zhong Q, Xu Y, Lei M, Chen R, Wang D, Li H, Wang H, Wang J, Shi Z, Cheng H.   +13 more
europepmc   +1 more source

Curcumin Alleviates the Osteogenesis Inhibition and the Aging Process in BMSCs Induced by Iron Overload Through Activating the NRF2/GPX4 Pathway

Phytotherapy Research, EarlyView.
Under iron overload conditions, curcumin inhibits cellular senescence and promotes osteogenic differentiation by activating the NRF2/GPX4 signaling pathway in bone marrow mesenchymal stem cells (BMSCs), thereby preventing the onset of osteoporosis. ABSTRACT Dysregulated proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs ...
Jingmin Che, Qing Feng, Zhixia Zhao, Jingying Sun, Weihao Ren, Yangmeng Feng, Cuixiang Xu, Xu‐Hui Li   +7 more
wiley   +1 more source

m⁶A-mediated stabilization of Bhlhe22 suppresses osteogenesis in osteoporosis by activating the PI3K-AKT-GSK3β signaling axis. [PDF]

Stem Cell Res Ther
Ye Q, Tao Q, Long X, Lou F, Li J, Li X, Tan D, Xiao J.   +7 more
europepmc   +1 more source

Hybrid Multiphoton Lithography Scaffolds for Nanoscale Mechanobiological Assessment in Microscale Bone Models

Small, EarlyView.
This work presents a 3D hybrid tissue scaffold inspired by bone, incorporating collagen, fabricated using multiphoton lithography. The mechanical properties of collagen are tunable, and biodegradation allows for time‐dependent changes in geometry. The results demonstrate enhanced osteogenic differentiation of stem cells in our hybrid scaffolds.
Christoph Naderer, Eleni Priglinger, Martina Ramsauer, Cornelia Bergmayr, Tobias Gotterbarm, Sofia Danilchenko, Dmitry Sivun, Jaroslaw Jacak   +7 more
wiley   +1 more source

Exosome-enabled bone defect repair: mechanistic foundations, bioengineered delivery, and artificial intelligence-driven translation. [PDF]

J Nanobiotechnology
Yang S, Ge S, Liu Z, Chen J, Chang F, Shen J, Wu F, Sun X, Wang Z, Li Y, Zhang M, Chen R, Feng T, Yin T, Fu P, Chen M, Yin P, Hao L.   +17 more
europepmc   +1 more source

Shape‐Memory Collagen/Silk‐Fibroin Scaffold for Dura Sealing and Skull Base Regeneration

Small, EarlyView.
ABSTRACT When a skull base defect occurs, reconstruction is typically performed using a variety of autologous grafts, flaps, or synthetic materials. Failure to achieve appropriate management and closure can lead to serious consequences, such as cerebrospinal fluid (CSF) leakage and subsequent meningitis.
SooJung Chae, Donghyeok Kim, Dongyun Kim, JaeYoon Lee, Sang Duk Hong, GeunHyung Kim   +5 more
wiley   +1 more source