Results 241 to 250 of about 145,083 (306)

Non‐Surgical Submarginal Instrumentation of Peri‐Implant Mucositis With Delivery of Sodium Hypochlorite/Amino Acids and Cross‐Linked Hyaluronic Acid: A Randomized Clinical Trial

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To evaluate the effects of submarginal instrumentation (SI) with or without adjunctive delivery of sodium hypochlorite (NaOCl)/amino acids and cross‐linked hyaluronic acid (xHyA) gel in the treatment of peri‐implant mucositis (PM).
Vincenzo Iorio‐Siciliano, Andrea Blasi, Leopoldo Mauriello, Peter Windisch, Giovanni E. Salvi, Anton Sculean, Luca Ramaglia   +6 more
wiley   +1 more source

Three-dimensional niche-like porous structure locoregionally regulating macrophage immunosenescence rejuvenates aged bone repair. [PDF]

Bioact Mater
Zhao DW, Fei X, Zhai H, Zhang Y, Hu R, Liu H, Li S, Kong X, Zhang Y, Zhang Z, Cheng L.   +10 more
europepmc   +1 more source

Lactate Accelerates Early Angiogenesis and Bone Regeneration Through Macrophage M1 Polarisation

Cell Proliferation, EarlyView.
During the early stage of bone defect healing, lactate accumulates and contributes to increasing NOD1 expression by stabilising HIF1α that in turn triggers a calcium influx, which ultimately polarises macrophages towards the M1 phenotype and accelerates vascularisation of endothelial cells.
Lulu Liu, Danning Ma, Jia Song, Boon Chin Heng, Ying Huang, Xuehui Zhang, Mingming Xu, Yan Wei, Tai Wei, Jinqi Wei, Xuliang Deng   +10 more
wiley   +1 more source

Genetically reprogrammed BMSCs with Lamin B1 depletion enhance bone regeneration for osteoporosis therapy. [PDF]

Front Bioeng Biotechnol
Fu X, Huo S, Cao C, Hsu H, Huang J, Lei Y, Li J, Liu P, Zeng J, Lin S, Liang C.   +10 more
europepmc   +1 more source

Validation of a Micro-CT Approach for Characterization of Murine and Human Bone in Osteogenesis Imperfecta [PDF]

, 2010
Harris, Gerald, Jameson, John, Molthen, Robert, Slavens, Brooke, Smith, Peter   +4 more
core   +1 more source

Single‐Cell Virtual Perturbation Screening Identifies STAT3 as a Key Regulator of Dentinogenesis

Cell Proliferation, EarlyView.
STAT3 promotes odontoblast differentiation in dental mesenchymal cells by transcriptionally regulating WNT2B via the canonical Wnt/β‐catenin signalling pathway. These findings elucidate a mechanism underlying dentine development. ABSTRACT Dentine formation constitutes a physiological process precisely regulated by signal transduction modules governing ...
Yanfei Zhu, Hongyuan Xu, Zijian Zhang, Siyuan Sun, Zihan Huang, Xin Gao, Houwen Pan, Xiangru Huang, Yuanqi Liu, Xinyu Wang, Hanbin Jia, Qinggang Dai, Lingyong Jiang   +12 more
wiley   +1 more source

Molecular mechanisms and preclinical evidence of natural products in diabetic osteoporosis: a review. [PDF]

Front Endocrinol (Lausanne)
Zhou T, Yu Y, Yang S, Xiao F, Yu R, Zhang G.   +5 more
europepmc   +1 more source

Unexpected Promotion of Bone Regeneration by Inhibition of BMPR1A‐Mediated BMP Signalling

Cell Proliferation, EarlyView.
BMPR1A downregulation reduces ID1, releases TCF3 to activate GNG4‐PI3K‐AKT signalling, thereby promoting OPC proliferation and bone regeneration. ABSTRACT Bone morphogenetic protein (BMP) signalling plays a pivotal role in bone regeneration by regulating osteoprogenitor cell (OPC) function, and BMPs have been widely used in clinical treatment. However,
Zihao Zhou, Yun Zhai, Xiaochen Liu, Jiaojiao Shao, Jiani Zhou, Zhaoyang Li, Jiale He, Shuxian Lin, Qi Zhang   +8 more
wiley   +1 more source

Synergistic osteogenesis, angiogenesis, and immune reprogramming by a metal-phenolic functionalized electrospun fibrous membrane for alveolar bone regeneration. [PDF]

Mater Today Bio
Zhou J, Hu Y, Bao J, Yang S, Zhu Y, Zhang Z, Chen M, Zhou Y, Lin K, Xu Y.   +9 more
europepmc   +1 more source

CKAP4 Regulates ERS‐Induced Apoptosis in Osteoclasts Through FOXO3 in Periodontitis

Cell Proliferation, EarlyView.
CKAP4 promotes the transcription of PERK via FOXO3 in OCs, thereby facilitating ER stress‐induced apoptosis. In periodontitis, the reduction of CKAP4 in OCs leads to decreased OC apoptosis, which exacerbates alveolar bone resorption. ABSTRACT Periodontitis is a prevalent oral disease characterised by chronic inflammation and irreversible alveolar bone ...
Jiayu Cheng, Dihao Tao, Wenzhe Wang, Huiyu Wang, Hanzhe Wang, Yufan Liang, Jia Guo, Wenhao Liu, Yiming Wang, Jianhua Yang, Xiaoning He, Ce Shan, Bei Li   +12 more
wiley   +1 more source