A Novel Long Noncoding RNA-LNC000133 Associated With Steroid-Induced Osteonecrosis of the Femoral Head Promotes Osteoblast Differentiation Through Bone Marrow Mesenchymal Stem Cells-Derived Exosomes Pathway: A Bioinformatics Validation and Detailed Mechanistic Study. [PDF]
Yang C, Xia T, Li X, Chen T, Xu Y.
europepmc +1 more source
Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li +5 more
wiley +1 more source
Hox Gene Variation Drives Morphological Specialization of Humpback Grouper Cromileptes altivelis
Cromileptes altivelis exhibits a distinctive “sunken head and humpback” morphology, formed through cranial remodeling. Genetic analyses identified unique amino acid variants in Hoxa7a and Hoxa10b, with functional tests confirming their role in enhancing osteoblast activity and driving cranial remodeling.
Xiaoying Cao +4 more
wiley +1 more source
Bone Quality in Resorbed Posterior Maxilla Affects Osteogenesis After Sinus Floor Augmentation: A Retrospective Analysis. [PDF]
Zhou W +4 more
europepmc +1 more source
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz +12 more
wiley +1 more source
Correction: Eruptive Process in Children with Osteogenesis Imperfecta. [PDF]
Garcete Delvalle CS +2 more
europepmc +1 more source
Congenital lipodystrophy induces severe osteosclerosis [PDF]
Brestoff, Jonathan R +10 more
core +1 more source
Pregnancies in women with rare diseases: Selected maternal and perinatal outcomes
Pregnancies in women with rare diseases carry substantial disease‐related (23.2%) and pregnancy‐specific (25.1%) risks. Complication rates drop markedly when conditions are stable before conception. Abstract Introduction Rare diseases (RD) are characterized by chronicity and may be associated with reduced life expectancy and quality of life.
Philipp Kosian +6 more
wiley +1 more source
Concurrent posterior vault expansion and extradural Chiari decompression in syndromic and non-syndromic craniosynostosis: a case series. [PDF]
Ryan IA +7 more
europepmc +1 more source

