Results 71 to 80 of about 165,191 (338)

Apolipoprotein D alleviates glucocorticoid-induced osteogenesis suppression in bone marrow mesenchymal stem cells via the PI3K/Akt pathway

Journal of Orthopaedic Surgery and Research, 2020
Background To clarify the role of apolipoprotein D (Apod) in alleviating glucocorticoid-induced osteogenesis suppression in bone marrow mesenchymal stem cells (MSCs) via the PI3K/Akt pathway, thus influencing the progression of osteoporosis (OP). Methods
Rong-Hua Yu, Xiang-yang Zhang, Wei Xu, Zhi-kun Li, Xiao-dong Zhu   +4 more
doaj   +1 more source

Nanoarchitecture‐Integrated Hydrogel Boosts Angiogenesis–Osteogenesis–Neurogenesis Tripling for Infected Bone Fracture Healing

Advancement of science
Infected fracture healing is a complicated process that includes intricate interactions at the cellular and molecular levels. In addition to angiogenesis and osteogenesis, the significance of neurogenesis in fracture healing has also been recognized in ...
Kang-Kang Zha, Weixian Hu, Yuan Xiong, Shengming Zhang, Mei-Jun Tan, Pengzhen Bu, Yan-Zhi Zhao, Wenqian Zhang, Ze Lin, Yi-Qiang Hu, Mohammad-Ali Shahbazi, Qian Feng, Guohui Liu, Bo-Bin Mi   +13 more
semanticscholar   +1 more source

Hybrid Biofabrication of a Hierarchically Organized Periosteum‐Inspired In Vitro Platform

Advanced Healthcare Materials, EarlyView.
A hybrid biofabrication strategy integrates melt electrowriting with extrusion‐based 3D bioprinting to create a hierarchically organized periosteum‐inspired in vitro platform. Spatially defined osteogenic, fibrous, and endothelial cell‐containing compartments support long‐term culture, osteogenic maturation, and CD31+ endothelial cell organization ...
Yakui Liu, Xinggui Tian, Anne Bernhardt, Anja Lode, Max von Witzleben, Ege Kirbas, Stefan Zwingenberger, Michael Gelinsky   +7 more
wiley   +1 more source

Factors Influencing Osteogenesis [PDF]

, 2023
The process of osteogenesis includes the well-coordinated proliferation and differentiation of osteogenic cells. It is known that mesenchymal stem cells are the progenitor cells in this process.
Kadreva, Nadezhda; Department of Anatomy, Histology and Embryology, Medical University-Plovdiv, Plovdiv, Bulgaria, Atanassova, Pepa; Department of Anatomy, Histology and Embryology, Medical University-Plovdiv, Plovdiv, Bulgaria, Georgieva, Elenka; Department of Developmental Biology, Plovdiv University “Paisii Hilendarski”, Faculty of Biology, Plovdiv, Bulgaria, Yancheva, Vesela; Department of Ecology and Environmental Conservation, Plovdiv University “Paisii Hilendarski”, Faculty of Biology, Plovdiv, Bulgaria, Stoyanova, Stela; Department of Developmental Biology, Plovdiv University “Paisii Hilendarski”, Faculty of Biology, Plovdiv, Bulgaria, Penkova, Nadya; Department of Anatomy, Histology and Embryology, Medical University-Plovdiv, Plovdiv, Bulgaria   +5 more
core   +1 more source

STAT3-mediated osteogenesis and osteoclastogenesis in osteoporosis

Cell communication and signaling : CCS, 2022
Osteoporosis is a common skeletal disease with marked bone loss, deterioration of the bone microstructure and bone fragility. An abnormal bone remodelling cycle with relatively increased bone resorption is the crucial pathophysiological mechanism.
Xiaoli S Hou, F. Tian
semanticscholar   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

Rheumatoid Arthritis-Like Hand Deformities in a Case with Osteogenesis Imperfecta: A Case Report [PDF]

, 2010
Summary Osteogenesis imperfecta is a disease that involves mesodermal tissues and characterized by decreased bone mass and increased bone fragility.
M. Fethi Ceylan, Levent Ediz, Yasemin Özkan, İbrahim Tekeoğlu, Özcan Hız   +4 more
core  

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage-Driven Inflammation and the TLR9/NF-κB Pathway. [PDF]

Adv Sci (Weinh)
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Gao H, Wu H, Li S, Wang W, Guo Y, Cheng S, Sun J, An J, Zhang W.   +8 more
europepmc   +2 more sources

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Intramedullary Nailing of Deformity and Fracture in a Patient with Osteogenesis Imperfecta

, 2014
Osteogenesis imperfecta is a hereditary disorder characterized by increased bone fragility. The production of type I collagen and endochondral bone development are disturbed.
Nevzat Dabak, Serdar Ulusoy, Hasan Göçer, Alper Çıraklı, İbrahim Kaya   +4 more
core   +1 more source