Results 61 to 70 of about 109,635 (268)

Rheumatoid Arthritis-Like Hand Deformities in a Case with Osteogenesis Imperfecta: A Case Report [PDF]

, 2010
Summary Osteogenesis imperfecta is a disease that involves mesodermal tissues and characterized by decreased bone mass and increased bone fragility.
M. Fethi Ceylan, Levent Ediz, Yasemin Özkan, İbrahim Tekeoğlu, Özcan Hız   +4 more
core  

Macrophages at Low-Inflammatory Status Improved Osteogenesis via Autophagy Regulation

, 2021
Accumulating evidence indicates that the interaction between immune and skeletal systems is vital in bone homeostasis. However, the detailed mechanisms between macrophage polarization and osteogenic differentiation of mesenchymal stromal cells (bone ...
Huang, Xin, Xiao, Lan, Xiao, Yin, Gao, Wendong, Yang, Lan, Zhang, Qing, Wei, Fei   +6 more
core   +1 more source

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

Advanced Science, EarlyView.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han, Jian‐sen Miao, Yi‐feng Shi, Yi‐ting Tu, Yu‐zhe Lin, Lin‐Jie Chen, Bing‐hao Lin, Hua‐lin Li, Xuan‐qi Zheng, Hong‐qiang Wu, Hai‐xiao Liu, Lei Yang, Ai‐min Wu, Zhen Lin, Jian Xiao, Gang Zheng, Chen Jin   +16 more
wiley   +1 more source

Spatial and temporal distribution of growth factors receptors in the callus: Implications for improvement of distraction osteogenesis [PDF]

, 2011
2011-08Management of bone deficits by distraction osteogenesis is an appreciated but lengthy procedure. To accelerate the consolidation of newly formed distraction callus, an administration of growth factors into the distraction gap has been suggested ...
Ishiguro, Naoki, Kitoh, Hiroshi, Kawasumi, Motoaki, Siwicka, Karolina A   +3 more
core   +1 more source

The role of the membrane of the maxillary sinus in space osteogenesis under the sinus floor after elevation of the sinus floor

口腔疾病防治, 2020
With the continuous development of maxillary sinus floor elevation technology, the osteogenesis mechanism of maxillary sinus floor elevation has always been a concern of scholars.
CHEN Songling, ZHU Shuangxi
doaj   +1 more source

Mechanical force induces macrophage-derived exosomal UCHL3 promoting bone marrow mesenchymal stem cell osteogenesis by targeting SMAD1

Journal of Nanobiotechnology, 2023
Background Orthodontic tooth movement (OTM), a process of alveolar bone remodelling, is induced by mechanical force and regulated by local inflammation. Bone marrow-derived mesenchymal stem cells (BMSCs) play a fundamental role in osteogenesis during OTM.
Panjun Pu, Shengnan Wu, Kejia Zhang, Hao Xu, Jiani Guan, Zhichun Jin, Wen Sun, Hanwen Zhang, Bin Yan   +8 more
doaj   +1 more source

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

Osobitosti anestezije kod ortopedskih zahvata u bolesnika s osteogenesis imperfecta [Characteristics of anesthesia in patients with osteogenesis imperfecta undergoing orthopedic surgical procedures] [PDF]

, 2014
The aim is to show our experience in anesthesia of patients with osteogenesis imperfecta (OI) who have undergone orthopedic surgical procedures. This is a retrospective analysis of OI patients treated at our Department from 1980 to 2012.
Buljan, Melita, Orešković, Zrinka, Kubat, Ozren, Antičević, Darko, Tripković, Branko, Jakovina-Blažeković, Sanja   +5 more
core   +1 more source

AI‐Assisted Engineering of Glycyrrhizic Acid/Simvastatin Nanocrystals for Multifunctional Treatment of Bacterial Osteomyelitis

Advanced Science, EarlyView.
Through AI‐assisted screening from FDA‐approved API to overcome the limitations of bacterial osteomyelitis treatment, glycyrrhizic acid and simvastatin are identified as a multifunctional combination capable of self‐assembling into mechanism‐targeting nanocrystals that effectively neutralize reactive oxygen species, suppress M1 macrophage polarization,
Yu Han, Yao Zhao, Chengbo Yang, Miao Niu, Jun Dai, Quanxin Ning, Kai Xiao, Jinzheng Liang, Wensheng Zhang, Liang Wang, Dan Shao, Dongsong Li   +11 more
wiley   +1 more source

Lithium and Copper Induce the Osteogenesis-Angiogenesis Coupling of Bone Marrow Mesenchymal Stem Cells via Crosstalk between Canonical Wnt and HIF-1α Signaling Pathways

Stem Cells International, 2021
The combination of osteogenesis and angiogenesis dual-delivery trace element-carrying bioactive scaffolds and stem cells is a promising method for bone regeneration and repair.
Zhen Tan, Baochun Zhou, Jianrui Zheng, Yongcan Huang, Hui Zeng, Lixiang Xue, Deli Wang   +6 more
doaj   +1 more source