Results 191 to 200 of about 10,653 (208)
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Osteoinduction by biomaterials—Physicochemical and structural influences
Journal of Biomedical Materials Research Part A, 2006AbstractOsteoinduction by biomaterials has been shown to be a real phenomenon by many investigators in the last decade. The exact mechanism of this phenomenon is, however, still largely unknown. This in vivo study in goats was performed to get insight into processes governing the phenomenon of osteoinduction by biomaterials and had four main goals: (i)
Habibovic, P +4 more
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Mechanisms of Osteoinduction/Chondroinduction by Demineralized Bone
Journal of Craniofacial Surgery, 2009Demineralized bone is widely used for osseous reconstructive procedures. Bone morphogenetic proteins (BMPs) have been studied as the putative active components of demineralized bone; recombinant BMPs are Food and Drug Administration-approved for use with scaffold carriers.
Julie, Glowacki +2 more
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The Osteoinductivity of Silicate-Substituted Calcium Phosphate
Journal of Bone and Joint Surgery, 2011The osteoinductivity of silicate-substituted calcium phosphate and stoichiometric calcium phosphate was investigated with use of ectopic implantation. Implants with a macroporosity of 80% and a strut porosity of 30% were inserted into sites located in the left and right paraspinal muscles of six female sheep.After twelve weeks in vivo, a longitudinal ...
Melanie J, Coathup +5 more
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Osteoinduction and its evaluation
2008Recently, there has been a vast interest in material-induced bone formation or material-directed osteoinduction. This is not only because osteoinduction is becoming a generally accepted phenomenon that can occur with a specific group of biomaterials, but also because of its potential clinical applicability. At this point of research and development, it
de Bruijn, J.D +3 more
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Osteoinduction with Colloss®, Colloss® E, and GFm
2007This study provided data relevant to three major goals. It confirmed that both COLLOSS and COLLOSS E contain osteo- and chondro-inductive BMPs as shown by their ability to produce new bone in an ectopic location in rats. Second, based on the area of bone produced in standardized implant sections by osteoinductive growth factors in GFm, COLLOSS , and ...
W E, Huffer +3 more
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Delivery Systems for Osteoinductive Proteins
1998Bone morphogenetic proteins (BMPs) have been investigated for three decades. The fact that demineralized bone and extracts of demineralized bone are osteoinductive was first shown by Urist [1]. The temporal sequence of bone induction was described by Reddi and co-workers [2].
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