Results 41 to 50 of about 8,219 (216)

Image_2_Resolvin D1 improves allograft osteointegration and directly enhances osteoblasts differentiation.jpeg [PDF]

, 2023
IntroductionAllografts are the most common bone grafts for repairing osseous defects. However, their use is associated with an increased risk for infections, donor disease transmission and osteointegration deficiency.
Gilad Mizrahi (14680054), Daniel Steinberg (2921043), Yasmin Khoury (14680057), Yechezkel Barenholz (202172), Stella Chaushu (175942), Noy Pinto (14680048), David Polak (175953), Yehuda Klein (13922649), Eilon David (14680051)   +8 more
core   +1 more source

Healthy and diabetic primary human osteoblasts exhibit varying phenotypic profiles in high and low glucose environments on 3D-printed titanium surfaces

Frontiers in Endocrinology
BackgroundThe revolution of orthopedic implant manufacturing is being driven by 3D printing of titanium implants for large bony defects such as those caused by diabetic Charcot arthropathy.
Nicholas Allen, Alexandra Hunter Aitchison, Bijan Abar, Julian Burbano, Mark Montgomery, Lindsey Droz, Richard Danilkowicz, Samuel Adams   +7 more
doaj   +1 more source

The Inhibition of Radial and Axial Micromovement of Bone Scaffold with Gelfoam^® and Titanium Mesh Fixation and Its Effects on Osteointegration

Methods and Protocols, 2019
A major drawback of nanocomposite scaffolds in bone tissue engineering is dimensional shrinkage after the fabrication process. Shrinkage yields gaps between the scaffold and host bone in the defect site and eventually causes failure in osteointegration ...
Jane Kwon, Dong Joon Lee, Mallory Kocher, Yong-Il Kim, Te-Ju Wu, John Whitley, Ching-Chang Ko   +6 more
doaj   +1 more source

Osteointegration of functionalised high-performance oxide ceramics: imaging from micro-computed tomography [PDF]

BackgroundThis study evaluated the osseointegration potential of functionalised high-performance oxide ceramics (HPOC) in isolation or coated with BMP-2 or RGD peptides in 36 New Zeeland female rabbits using micro-computed tomography (micro CT).
Maffulli, Nicola, Migliorini, Filippo, Hildebrand, Frank, Rath, Björn, Sophie Lecouturier, Hanno Schenker, Schenker, Hanno, Eschweiler, Jörg, Björn Rath, Tingart, Markus, Nicola Maffulli, Frank Hildebrand, Markus Tingart, Marcel Betsch, Filippo Migliorini, Betsch, Marcel, Jörg Eschweiler, Lecouturier, Sophie   +17 more
core   +2 more sources

Enhanced osteointegration of tantalum-modified titanium implants with micro/nano-topography [PDF]

, 2017
Ta modification enhanced the osteointegration of an SLA surface with micro/nano topography and the possible mechanism might be activation of the Wnt pathway.
Xiaomeng Zhang, Jiaji Mo, Shichong Qiao, Yingxin Gu, Hongchang Lai, Jie Ni, Junyu Shi   +6 more
core   +1 more source

Kappa-carrageenan-Functionalization of octacalcium phosphate-coated titanium Discs enhances pre-osteoblast behavior and osteogenic differentiation

Frontiers in Bioengineering and Biotechnology, 2022
Bioactive coatings are promising for improving osseointegration and the long-term success of titanium dental or orthopaedic implants. Biomimetic octacalcium phosphate (OCP) coating can be used as a carrier for osteoinductive agents.
Wei Cao, Wei Cao, Jianfeng Jin, Gang Wu, Nathalie Bravenboer, Marco N. Helder, Engelbert A. J. M. Schulten, Rommel G. Bacabac, Janak L. Pathak, Jenneke Klein-Nulend   +9 more
doaj   +1 more source

An Ion‐Based Strategy Toward Synergistic Surface Functionalization Combining the Osteogenic Properties and NIR‐Mediated Antibacterial Activity of PEEK

Advanced Materials, EarlyView.
A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu, Ondřej Adam, Marek Doubrava, Ana M. Beltrán, Ivo Dlouhý, Xin Liu, Baiyan Sui, Aldo R. Boccaccini   +7 more
wiley   +1 more source

Clinical Evaluation of the Osteointegration [PDF]

, 2002
INTRODUCTION: The treatment of the complete or partially edentulous patient with a prothesis supported by dental implants is a procedure with high predictability. Themost important factor is the osteointegration of the implant.
MA. Banos, JA. Martinez, Banos, MA., Martinez, JA.   +3 more
core   +1 more source

Deep Learning Network‐Tailored Microenvironment Matching of 4D Bioprinting Bioactive Scaffolds for Bone Regeneration

Advanced Science, EarlyView.
A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang, Yuechi Zhang, Weifeng Hu, Shiyan Lv, Fan Jia, Yan Zhang, Feng Wu, Changjiang Yang, Guanqi Zhen, Jinglong Yan, Xu Cui, Wei Zhao, Guanghua Chen   +12 more
wiley   +1 more source

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

Advanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei, Yogambha Ramaswamy, Young Jung No   +2 more
wiley   +1 more source