Results 61 to 70 of about 130,738 (311)

Consensus Treatment Plans for Chronic Nonbacterial Osteomyelitis Refractory to Nonsteroidal Antiinflammatory Drugs and/or With Active Spinal Lesions

Arthritis care & research, 2018
To develop standardized treatment regimens for chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO), to enable comparative effectiveness treatment studies.
Yongdong Zhao, E. Wu, M. Oliver, Ashley M. Cooper, M. Basiaga, S. Vora, Tzielan Lee, E. Fox, G. Amarilyo, S. Stern, J. Dvergsten, K. Haines, K. Rouster-Stevens, K. Onel, J. Cherian, J. Hausmann, P. Miettunen, T. Cellucci, F. Nuruzzaman, A. Taneja, K. Barron, M. Hollander, S. Lapidus, Suzanne C. Li, S. Ozen, H. Girschick, R. Laxer, F. Dedeoğlu, C. Hedrich, P. Ferguson   +29 more
semanticscholar   +1 more source

Research Progress on Biomaterials with Immunomodulatory Effects in Bone Regeneration

Advanced Science, EarlyView.
This review highlights recent advanced in immunomodulatory biomaterials for bone repair, focusing on design strategies, immune interactions, and clinical potential. Abstract The immune system plays a pivotal role in bone regeneration, and biomaterials engineered to modulate immune responses present a promising strategy for the treatment of extensive ...
Jianan Li, Ying Qu, Bingyang Chu, Tingkui Wu, Meng Pan, Dong Mo, Lang Li, Yang Ming, Yun Yang, Meng Wang, Xinlong He, Zhiyong Qian   +11 more
wiley   +1 more source

Correlation Analysis between Chronic Osteomyelitis and Bacterial Biofilm

Stem Cells International, 2022
Objective. To study the role of bacterial biofilm (BBF) in the formation of chronic osteomyelitis and its prevention and treatment. Methods. In this paper, a large amount of relevant literature was searched for analysis and summary, and the key words ...
Kai Huang, Bingyuan Lin, Yiyang Liu, Haiyong Ren, Qiaofeng Guo   +4 more
doaj   +1 more source

The effect of Staphylococcus aureus on innate and adaptive immunity and potential immunotherapy for S. aureus-induced osteomyelitis

Frontiers in Immunology, 2023
Osteomyelitis is a chronic inflammatory bone disease caused by infection of open fractures or post-operative implants. Particularly in patients with open fractures, the risk of osteomyelitis is greatly increased as the soft tissue damage and bacterial ...
Yingqi Chen, Yingqi Chen, Zixian Liu, Zixian Liu, Zexin Lin, Zexin Lin, Mincheng Lu, Mincheng Lu, Yong Fu, Yong Fu, Yong Fu, Guanqiao Liu, Guanqiao Liu, Bin Yu, Bin Yu   +14 more
doaj   +1 more source

A Herbal‐Piezoelectric Heterojunction Strategy to Potentiate Bacterial Cuproptosis‐Like Death and Remodel the Inflammatory Microenvironment in Infection‐Associated Implant Osteomyelitis

Advanced Science, EarlyView.
A titanium implant coating integrating berberine and copper‐doped strontium titanate leverages ultrasound to compromise bacterial membranes and induce cuproptosis‐like death. This approach resolves S. aureus infections in osteomyelitis models while suppressing inflammation and promoting osseointegration, demonstrating a dual‐functional strategy against
Guannan Zhang, Zehao Li, Ying Lu, Jianbo Song, Xingyu Liang, Peide Han, Xiaohong Yao, Yongqiang Yang, Xiangyu Zhang   +8 more
wiley   +1 more source

Distally based sural flaps for soft tissue defects following traumatic osteomyelitis of lower leg and foot

Scientific Reports
This retrospective study aimed to determine the incidence and risk factors for osteomyelitis recurrence and present our experiences in treating traumatic osteomyelitis in the lower leg and foot.
Shunhong Luo, Yingliang Jiang, Zhonggen Dong, Xiao Peng, Shimu Shi, Zhaobiao Luo, Shibin Tao, Jianwei Wei   +7 more
doaj   +1 more source

Real-World Use of Oritavancin for the Treatment of Osteomyelitis

Drugs - Real World Outcomes, 2020
Osteomyelitis is a difficult-to-treat disease that can require both surgical debridement and a prolonged course of antimicrobial therapy. Current standard of care for the antimicrobial treatment of osteomyelitis is fraught with multiple challenges and ...
Patrick J. Scoble, Joseph Reilly, Glenn S. Tillotson   +2 more
doaj   +1 more source

Biocompatible Mesoporous Materials for Bone Therapy

Advanced Science, EarlyView.
Biocompatible mesoporous materials (BMMs), characterized by high specific surface area, tunable pore size, different shapes and structures, and multidimensional functionalized modifications, have revolutionary applications in treating bone‐related diseases.
Biao Yu, Yan Wu, Yang Hong, Peng Wang, Xiaowen Liu, Yonghui Deng, Jiacan Su   +6 more
wiley   +1 more source

CRISPR-Cas9 modified bacteriophage for treatment of Staphylococcus aureus induced osteomyelitis and soft tissue infection

bioRxiv, 2019
Osteomyelitis, or bone infection, is often induced by antibiotic resistant Staphylococcus aureus strains of bacteria. Although debridement and long-term administration of antibiotics are the gold standard for osteomyelitis treatment, the increase in ...
Leah K. Horstemeyer, J. Park, E. A. Swanson, Mary Catherine Beard, Emily M McCabe, Anna S. Rourke, K. Seo, A. Olivier, L. Priddy   +8 more
semanticscholar   +1 more source

Osteomyelitis of the calcaneum [PDF]

The Journal of Bone and Joint Surgery. British volume, 1992
We reviewed 52 cases of osteomyelitis of the calcaneum. The clinical symptoms and signs were well defined, but different and less dramatic than those of long-bone osteomyelitis. Blood cultures were positive in 41% of cases and tissue cultures in 91%.
G. C. Bennet, S. Simpson, Edward H. M. Wang   +2 more
openaire   +3 more sources