Results 61 to 70 of about 28,897 (199)

Real-World Use of Oritavancin for the Treatment of Osteomyelitis

Drugs - Real World Outcomes, 2020
Osteomyelitis is a difficult-to-treat disease that can require both surgical debridement and a prolonged course of antimicrobial therapy. Current standard of care for the antimicrobial treatment of osteomyelitis is fraught with multiple challenges and ...
Patrick J. Scoble, Joseph Reilly, Glenn S. Tillotson   +2 more
doaj   +1 more source

Crestal approach for repair of oroantral bone defects and subsequent implant placement

Clinical Advances in Periodontics, EarlyView.
Abstract Background Oroantral communication (OAC) can occur after a dental extraction. Occasionally, bony defects may persist despite successful soft tissue closure of the OAC. The absence of bone in these areas poses challenges for dental implant placement.
Min Yang, Miriam Ting, Rodrigo Neiva, Jonathan Korostoff   +3 more
wiley   +1 more source

Citrus Flavonoids as Antimicrobials

Chemistry &Biodiversity, EarlyView.
Citrus flavonoids are powerful and versatile antimicrobials whose mechanism of action often involves disruption of the bacterial membrane, thereby minimizing antimicrobial resistance. This study provides a unified perspective. ABSTRACT Citrus flavonoids are highly bioactive compounds exerting numerous health benefits including anticancer, antioxidant ...
Rosaria Ciriminna, Giovanna Li Petri, Giuseppe Angellotti, Rafael Luque, Anne‐Sylvie Fabiano Tixier, Francesco Meneguzzo, Mario Pagliaro   +6 more
wiley   +1 more source

Chronic femoral diaphyseal osteomyelitis with radiographs initially concerning for Paget disease of the bone

Radiology Case Reports, 2020
Chronic osteomyelitis can be difficult to diagnose given its similar radiographic appearance to other lesions. This case report describes a 48-year-old woman, who presented with left thigh pain and on radiography a large disorganized sclerotic lesion ...
Seth A. Reasoner, BA, Juan M. Colazo, BSc, Jonathan Tucci, MD, PhD, Justin Cates, MD, PhD, Kathryn M. Dahir, MD   +4 more
doaj  

Factors predictive of relapse in adult bacterial osteomyelitis of long bones.

BMC Infectious Diseases, 2018
Background Osteomyelitis is a difficult-to-cure infection with a high relapse rate despite combined medical and surgical therapies. Some severity factors, duration of antimicrobial therapy and type of surgical procedure might influence osteomyelitis ...
E. Garcia del Pozo, J. Collazos, J. A. Carton, D. Camporro, V. Asensi   +4 more
doaj   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

Exploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang, Shuihao Zhao, Haijie Zhao, Mingzhang Wen, Zhong Guo   +4 more
wiley   +1 more source

Causal associations between human gut microbiota and osteomyelitis: a Mendelian randomization study

Frontiers in Cellular and Infection Microbiology
BackgroundRecent studies have emphasized the role of gut microbiota in the onset and progression of osteomyelitis. However, the exact types of gut microbiota and their mechanisms of action remain unclear.
Wenxing Zeng, Yuheng Wu, Yuheng Wu, Xiaoye Liang, Dejun Cun, Luyao Ma, Jingtao Zhang, Feng Huang, Feng Huang, Ziwei Jiang, Ziwei Jiang   +10 more
doaj   +1 more source

PECULIAR IMMUNOLOGICAL PROPERTIES OF CHRONIC POSTTRAUMATIC OSTEOMYELITIS

Travmatologiâ i Ortopediâ Rossii, 2012
A comparative study of cellular immunity parameters was performed in patients with long bone chronic posttraumatic osteomyelitis in regard to osteomyelitis stages.
M. V. Chepeleva, N. M. Klyushin
doaj   +1 more source

Membrane Filtration of Sonication Fluid—A Promising Adjunctive Method for the Diagnosis of Low‐Grade Infection in Presumed Aseptic Nonunion

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Treatment guidelines for fracture nonunion differ based on the presence or absence of infection. Low‐grade infections without preoperative clinical signs of infection are difficult to distinguish from aseptic cases. Membrane filtration of sonication fluid (MF) has been shown to be a useful method for identifying septic nonunion. Therefore, the
Katharina Trenkwalder, Sandra Erichsen, Ferdinand Weisemann, Peter Augat, SAND Research Group, Simon Hackl, Matthias Militz, Simon Hackl, Ferdinand Weisemann, Katharina Trenkwalder, Sandra Erichsen, Tobias Hentschel, Peter Augat, Heiko Baumgartner, Marie Reumann, Georg Reiter, Holger Freischmidt, Matthias Kemmerer, Steffen Langwald, John Hanke, Martin Glombitza, Eva Steinhausen, Ulf‐Joachim Gerlach, Nikolai Spranger, Dirk Stengel   +24 more
wiley   +1 more source

Clinical presentation, treatment, and outcome of 24 dogs with bacterial meningitis or meningoencephalitis without empyema (2010‐2020)

Journal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 223-229, January/February 2023., 2023
Abstract Background Bacterial meningitis (BM) and meningoencephalitis (BMEM) are associated with high case fatality rates and neurologic sequelae in people, but limited data exists on outcome in dogs. Hypothesis/Objectives To report the clinicopathologic features, treatment and outcome of BM/BMEM in dogs, with a focus on clinical presentation, relapse ...
Faye Rawson, Max Foreman, Thomas Mignan, Jack Galer, Anne Fraser, Abbe Crawford   +5 more
wiley   +1 more source