Results 71 to 80 of about 44,473 (251)

Low Oxygen Tension Enhances Osteogenic Potential of Bone Marrow-Derived Mesenchymal Stem Cells with Osteonecrosis-Related Functional Impairment

Stem Cells International, 2015
Objective. Glucocorticoids can affect the function of bone marrow-derived mesenchymal stem cells (BMMSCs) adversely and merit the requirement for a strategy to correct this anomaly; we assessed the effect of low oxygen (2%) on BMMSCs from rabbits with ...
Lihong Fan, Ruiyu Liu, Jia Li, Zhibin Shi, Xiaoqian Dang, Kunzheng Wang   +5 more
doaj   +1 more source

Current Animal Models of Postoperative Spine Infection and Potential Future Advances. [PDF]

, 2015
Implant related infection following spine surgery is a devastating complication for patients and can potentially lead to significant neurological compromise, disability, morbidity, and even mortality.
Bernthal, NM, Dworsky, EM, Hu, Y, Loftin, AH, Lord, EL, Manegold, JE, Scaduto, AA, Stavrakis, AI   +7 more
core   +1 more source

In Vitro Evaluation of Hemiarthroplasty Bearing Materials: A Scoping Review (Part I)

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Hemiarthroplasty is used to treat joint damage confined to one side, aiming to preserve the remaining healthy cartilage and bone while addressing conditions like femur fractures and osteonecrosis; however, challenges persist due to cartilage wear and inconsistent clinical outcomes.
Victoria P. Marino, Francesca De Vecchi, Takayuki Koya, Landon M. Begin, Douglas C. Moore, Joseph J. Crisco, Markus A. Wimmer   +6 more
wiley   +1 more source

Combined Therapy with Shock Wave and Retrograde Bone Marrow-Derived Cell Transplantation for Osteochondral Lesions of the Talus

Scientific Reports, 2017
Multiple treatment strategies have been developed for osteochondral lesions (OCLs) of the talus. The purpose of this retrospective study was to assess retrograde autologous bone marrow cell (BMC) transplantation via core drilling (CD) combined with ...
Fuqiang Gao, Na Chen, Wei Sun, Bailiang Wang, Zhencai Shi, Liming Cheng, Zirong Li, Wanshou Guo   +7 more
doaj   +1 more source

Association between the ossific nucleus and osteonecrosis in treating developmental dysplasia of the Hip: updated meta-analysis. [PDF]

, 2017
BACKGROUND: A meta-analysis concluded that there was no effect of the femoral head ossification and the incidence of osteonecrosis in the treatment of developmental dysplasia of the hip (DDH), unless only osteonecrosis grades II-IV were considered.
Elvey, Michael, Niziol, Rafal, Protopapa, Evangelia, Roposch, Andreas   +3 more
core   +2 more sources

Peri‐implant inflammation increases the risk of osteonecrosis in mice treated with bisphosphonate

Journal of Periodontology, EarlyView.
Abstract Background Bisphosphonates (BPs) are effective in managing bone diseases due to their anti‐resorptive properties but are linked to medication‐related osteonecrosis of the jaw (MRONJ), particularly concerning dental implants. This study explored the combined impact of ligature‐induced peri‐implant inflammation and zoledronic acid (ZA), a BP ...
Ana Bujila, Davi N. A. Silva, Sepehr Monajemzadeh, Taciane M. da Silveira, Naseim Elzakra, Maísa Casarin, Kimberly Flores, Clara Magyar, Julie Marchesan, Reuben Kim, Sotirios Tetradis, Flavia Q. Pirih   +11 more
wiley   +1 more source

First report of multi-drug resistant tuberculosis in a systemic lupus erythematosus patient. [PDF]

, 2015
BackgroundTreatment of a multi-drug resistant tuberculosis (MDR-TB) patient is clinically challenging, requiring a minimum of 18 months of therapy. Its occurrence in a systemic lupus erythromatosus (SLE) patient may complicate management of both MDR-TB ...
Dierberg, Kerry L, Dorjee, Kunchok, Reingold, Arthur L, Sadutshang, Tsetan D   +3 more
core   +1 more source

Cemented mobile‐bearing medial unicompartmental knee arthroplasty provides long‐term implant survival and sustained functional performance in young and active patients aged 60 or below

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate long‐term outcomes of cemented, mobile‐bearing medial unicompartmental knee arthroplasty (UKA) in patients aged 60 or younger, focusing on implant survival, functional results, patient‐reported outcome measures (PROMs), and radiographic findings over >10 years.
Kevin‐Arno Koch, Michael Thapa, Johannes Weishorn, Mustafa Hariri, Benedict Lotz, Kevin Knappe, Tobias Reiner, Tilman Walker   +7 more
wiley   +1 more source

Osteonecrosis of the Hip: A Primer [PDF]

The Permanente Journal, 2019
In this report, we deliver a concise and up-to-date review of osteonecrosis, a pathologic, painful, and often disabling condition that is believed to result from the temporary or permanent disruption of blood supply to an affected area of bone. We will discuss the epidemiology (disease distribution), pathogenesis (mechanism of development), etiology ...
Michael A. Mont, Nipun Sodhi, Michelle J Lespasio   +2 more
openaire   +3 more sources

Patients with preoperative bone marrow oedema benefit more substantially from medial meniscus posterior root repair

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To analyze the clinical outcomes of the surgical repair of medial meniscus posterior root tear (MMRT) in patients with preoperative bone marrow oedema (BME). Methods Patients who underwent arthroscopic pull‐out repair for MMRT between 2010 and 2022 were retrospectively reviewed, and those with a minimum of two years of follow‐up were ...
Junwoo Byun, Sung‐Hwan Kim, Chong‐Hyuk Choi, Min Jung, Kwangho Chung, Se‐Han Jung, Jun‐Young Lim, Hyun‐Soo Moon   +7 more
wiley   +1 more source