Results 71 to 80 of about 72,632 (272)
Semaphorin 4D Promotes Skeletal Metastasis in Breast Cancer. [PDF]
, 2016 Bone density is controlled by interactions between osteoclasts, which resorb bone, and osteoblasts, which deposit it. The semaphorins and their receptors, the plexins, originally shown to function in the immune system and to provide chemotactic cues for ...
Basile, John R +6 more
core +2 more sources
Stem Cells International, 2015 Objective. Glucocorticoids can affect the function of bone marrow-derived mesenchymal stem cells (BMMSCs) adversely and merit the requirement for a strategy to correct this anomaly; we assessed the effect of low oxygen (2%) on BMMSCs from rabbits with ...
Lihong Fan +5 more
doaj +1 more source
Knee arthroplasty failure is associated with significant systemic multimetal exposure
Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.Abstract Purpose This study investigated whether patients scheduled for revision total knee arthroplasty (TKA) are systemically exposed to arthroplasty metals, and whether systemic metal levels in these patients differ depending on the implants' levels of constraint.
Anna Flindt +8 more
wiley +1 more source
Intratumoral Nerve Phased Development: A Promising Therapeutic Target
Medicine Bulletin, EarlyView.ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che +3 more
wiley +1 more source
Scientific Reports, 2017 Multiple treatment strategies have been developed for osteochondral lesions (OCLs) of the talus. The purpose of this retrospective study was to assess retrograde autologous bone marrow cell (BMC) transplantation via core drilling (CD) combined with ...
Fuqiang Gao +7 more
doaj +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Osteoporosis, characterized by osteoclastic bone resorption, has been the focus of research. Studies implicate that reactive oxygen species (ROS) accumulate intracellularly during osteoclastogenesis. Salvianolic acid A (SAA), a compound derived from Salvia miltiorrhiza, has been widely used to treat cardiovascular and cerebrovascular disorders,
Hao Qiu +5 more
wiley +1 more source
Immunomodulatory Biomaterials for Bone and Soft Tissue Chronic Inflammation Diseases
Small Science, EarlyView.This review analyzes immunomodulatory biomaterial strategies for treating chronic inflammatory disorders in bone and soft tissues. It explores emerging mechanisms for resolving inflammation while promoting tissue regeneration, offering insights for developing targeted immunotherapeutic approaches that bridge material science with immunology for ...
Yiming Li +7 more
wiley +1 more source
Dental extraction following zoledronate, induces osteonecrosis in rat´s jaw [PDF]
, 2017 Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) is clinically characterized by the presence of exposed bone in the oral cavity that persists for more than eight weeks.
Gaitán Cepeda, Luis Alberto +2 more
core +1 more source
Small Methods, EarlyView.This work presents an integrated set of methods to evaluate the efficacy of asparaginase formulations against B‐cell Acute Lymphoblastic Leukemia (ALL) in mice, including the establishment of an ALL murine model, an amino acid depletion study using high‐performance liquid chromatography (HPLC), and comprehensive assessment of antibody production ...
Julien Santelli +6 more
wiley +1 more source
Which Osteotomy for Osteonecrosis of the Femoral Head and Which Patient for the Osteotomy? [PDF]
, 2019 Transtrochanteric curved varus osteotomy (TCVO) and transtrochanteric rotational osteotomy (TRO) are joint-preserving procedures for osteonecrosis of the femoral head.
Ha, Yong-Chan +4 more
core +1 more source