Results 71 to 80 of about 73,209 (288)

Aggravated bone density decline following symptomatic osteonecrosis in children with acute lymphoblastic leukemia

open access: yesHaematologica, 2015
Osteonecrosis and decline of bone density are serious side effects during and after treatment of childhood acute lymphoblastic leukemia. It is unknown whether osteonecrosis and low bone density occur together in the same patients, or whether these two ...
Marissa A.H. den Hoed   +14 more
doaj   +1 more source

General recommendation for assessment and management on the risk of glucocorticoid-induced osteonecrosis in patients with COVID-19

open access: yesJournal of Orthopaedic Translation, 2021
Background/objective: Coronavirus disease 2019 (COVID-19) is a disaster in human medical history and glucocorticoids remain the most promising therapy.
Wenlong Li   +30 more
doaj   +1 more source

Perioperative Piperacillin/Tazobactam Reduces Early Onset SSI in Preirradiated Patients Undergoing Microvascular Head and Neck Reconstruction

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Preirradiated patients undergoing microvascular head and neck reconstruction for tumor recurrence or osteoradionecrosis (ORN) face surgical site infection (SSI) rates exceeding 30%. The impact of perioperative extended‐spectrum antibiotic coverage remains unclear. This study hypothesizes that calculated prophylaxis with piperacillin/
Johannes G. Schuderer   +11 more
wiley   +1 more source

Combined Therapy with Shock Wave and Retrograde Bone Marrow-Derived Cell Transplantation for Osteochondral Lesions of the Talus

open access: yesScientific Reports, 2017
Multiple treatment strategies have been developed for osteochondral lesions (OCLs) of the talus. The purpose of this retrospective study was to assess retrograde autologous bone marrow cell (BMC) transplantation via core drilling (CD) combined with ...
Fuqiang Gao   +7 more
doaj   +1 more source

Low Oxygen Tension Enhances Osteogenic Potential of Bone Marrow-Derived Mesenchymal Stem Cells with Osteonecrosis-Related Functional Impairment

open access: yesStem Cells International, 2015
Objective. Glucocorticoids can affect the function of bone marrow-derived mesenchymal stem cells (BMMSCs) adversely and merit the requirement for a strategy to correct this anomaly; we assessed the effect of low oxygen (2%) on BMMSCs from rabbits with ...
Lihong Fan   +5 more
doaj   +1 more source

Osteocyte dysfunction promotes osteoarthritis through MMP13-dependent suppression of subchondral bone homeostasis. [PDF]

open access: yes, 2019
Osteoarthritis (OA), long considered a primary disorder of articular cartilage, is commonly associated with subchondral bone sclerosis. However, the cellular mechanisms responsible for changes to subchondral bone in OA, and the extent to which these ...
Acevedo, Claire   +12 more
core  

Semaphorin 4D Promotes Skeletal Metastasis in Breast Cancer. [PDF]

open access: yes, 2016
Bone density is controlled by interactions between osteoclasts, which resorb bone, and osteoblasts, which deposit it. The semaphorins and their receptors, the plexins, originally shown to function in the immune system and to provide chemotactic cues for ...
Basile, John R   +6 more
core   +2 more sources

Patients with preoperative bone marrow oedema benefit more substantially from medial meniscus posterior root repair

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To analyze the clinical outcomes of the surgical repair of medial meniscus posterior root tear (MMRT) in patients with preoperative bone marrow oedema (BME). Methods Patients who underwent arthroscopic pull‐out repair for MMRT between 2010 and 2022 were retrospectively reviewed, and those with a minimum of two years of follow‐up were ...
Junwoo Byun   +7 more
wiley   +1 more source

Posterior femoral condylar morphology following mechanical vs. kinematic alignment using a medial‐pivot implant designed for mechanical alignment: A CT‐based comparative study

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The kinematic alignment (KA) technique aims to restore native joint anatomy; however, the extent to which it restores posterior femoral condylar morphology after total knee arthroplasty (TKA) remains unclear. The posterior longitudinal overhang in the femoral condyle (PLOF) has been reported to affect clinical outcomes.
Yohei Ohyama   +5 more
wiley   +1 more source

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