Results 31 to 40 of about 21,214 (278)

Predicting the collapse of the femoral head due to osteonecrosis: From basic methods to application prospects

Journal of Orthopaedic Translation, 2017
Collapse of the femoral head is the most significant pathogenic complication arising from osteonecrosis of the femoral head. It is related to the disruption of the maintenance of cartilage and bone, and results in an impaired function of the vascular ...
Leilei Chen, GuoJu Hong, Bin Fang, Guangquan Zhou, Xiaorui Han, Tianan Guan, Wei He   +6 more
doaj   +1 more source

A Rabbit Model of Avascular Necrosis of Femoral Head Using Surgical Trauma and Systemic Steroids

Bezmiâlem Science, 2020
Objective:Avascular necrosis of the femoral head (ANFH) is a disease caused by the diminished circulation of the femoral head. The incidence of the disease is increasing and it has heavy socioeconomical burden.
Hakan ÖZBEN
doaj   +1 more source

Decreased levels of insulin-like growth factor-1 and vascular endothelial growth factor relevant to the ossification disturbance in femoral heads spontaneous hypertensive rats. [PDF]

, 2006
Ossification disturbance in femoral head reportedly is seen in the Spontaneously Hypertensive rats (SHR) between ages of 10 and 20 weeks. We investigated serum and tissue levels of insulin-like growth factor-1 (IGF-1) and vascular endothelial growth ...
Abe, Nobuhiro, Doi, Hideyuki, Kitamura, Ai, Komiyama, Takamitsu, Miyazawa, Shinichi, Nasu, Yoshihisa, Nishida, Keiichiro, Ozaki, Toshifumi, Yorimitsu, Masanori, Yoshida, Aki   +9 more
core   +1 more source

AAV-Anti-miR-214 Prevents Collapse of the Femoral Head in Osteonecrosis by Regulating Osteoblast and Osteoclast Activities

Molecular Therapy: Nucleic Acids, 2019
Osteonecrosis of the femoral head, an intractable but common disease that eventually triggers collapse of the femoral head, is characterized by increased osteoclast activity and markedly decreased osteoblast activity in the necrotic region of the femoral
Cheng Wang, Weijia Sun, Shukuan Ling, Yu Wang, Xin Wang, Haoye Meng, Yuheng Li, Xueling Yuan, Jianwei Li, Ruoxi Liu, Dingsheng Zhao, Qiang Lu, Aiyuan Wang, Quanyi Guo, Shibi Lu, Hua Tian, Yingxian Li, Jiang Peng   +17 more
doaj   +1 more source

Accuracy of MRI diagnosis of early osteonecrosis of the femoral head: a meta-analysis and systematic review

Journal of Orthopaedic Surgery and Research, 2018
Objective To evaluate the overall diagnostic value related to magnetic resonance imaging (MRI) in patients with early osteonecrosis of the femoral head. Methods By searching multiple databases and sources, including PubMed, Cochrane, and Embase database,
Ya-Zhou Zhang, Xu-Yang Cao, Xi-Cheng Li, Jia Chen, Yue-Yuan Zhao, Zhi Tian, Wang Zheng   +6 more
doaj   +1 more source

Hip preserving surgery with concentrated autologous bone marrow aspirate transplantation for the treatment of asymptomatic osteonecrosis of the femoral head: retrospective review of clinical and radiological outcomes at 6 years postoperatively [PDF]

, 2017
BackgroundWe had previously established concentrated autologous bone marrow aspirate transplantation (CABMAT), a one-step, low-invasive, joint-preserving surgical technique for treating osteonecrosis of the femoral head (ONFH). The present study aimed to
Akaogi Hiroshi, Aoto Katsuya, Mishima Hajime, Sugaya Hisashi, Tomaru Yohei, Wada Hiroshi, Yamazaki Masashi, Yoshioka Tomokazu, 吉岡 友和   +8 more
core   +2 more sources

Spontaneous femoral neck fracture resulting from osteonecrosis involving lateral femoral head-neck junction: a retrospective study

BMC Musculoskeletal Disorders, 2023
Background Spontaneous femoral neck fracture is a rare condition that remains controversial due to limited reported cases. This retrospective study aims to provide further insights into the etiology and characteristics of the disease. Method We conducted
Xin Guo, Yihui Zeng, Haijun Xu, Xinyuan Zhan   +3 more
doaj   +1 more source

Dose-dependent new bone formation by extracorporeal shock wave application on the intact femur of rabbits [PDF]

, 2008
Background: Whereas various molecular working mechanisms of shock waves have been demonstrated, no study has assessed in detail the influence of varying energy flux densities (EFD) on new bone formation in vivo. Methods: Thirty Chinchilla bastard rabbits
Hausdorf, J., Maier, M., Milz, S., Pautke, C., Schmitz, C., Tischer, T., Weiler, C.   +6 more
core   +1 more source

Vascularity of femoral head and its assessment after femoral neck fractures

Journal of Orthopaedic Diseases and Traumatology, 2018
Femoral neck fracture has an annual incidence of 1 per 1000 population; in young patients, functional prognosis is not good due to risk of osteonecrosis. Femoral head vascularity is mostly contributed by retinacular vessels and lateral epiphyseal artery.
Harshal Sakale, Alok C Agrawal, Bikram Keshri Kar, Bikas Sahoo, Sandeep K Yadav   +4 more
doaj   +1 more source

Proper mechanical stress promotes femoral head recovery from steroid-induced osteonecrosis in rats through the OPG/RANK/RANKL system

BMC Musculoskeletal Disorders, 2020
Background Long-term use of steroid may lead to osteonecrosis of the femoral head (ONFH). Mechanical stress may help bone formation and remodeling. This study aimed to probe the role of mechanical stress in the femoral head recovery in rats.
Dapeng Fu, Kairong Qin, Sheng Yang, Jianmin Lu, Haoyi Lian, Dewei Zhao   +5 more
doaj   +1 more source