New insights into the biomechanics of Legg-Calvé-Perthes’ disease: The role of epiphyseal skeletal immaturity in vascular obstruction [PDF]
ObjectivesLegg–Calvé–Perthes’ disease (LCP) is an idiopathic osteonecrosis of the femoral head that is most common in children between four and eight years old.
Dobson, C. A. +3 more
core +1 more source
Decreased levels of insulin-like growth factor-1 and vascular endothelial growth factor relevant to the ossification disturbance in femoral heads spontaneous hypertensive rats. [PDF]
Ossification disturbance in femoral head reportedly is seen in the Spontaneously Hypertensive rats (SHR) between ages of 10 and 20 weeks. We investigated serum and tissue levels of insulin-like growth factor-1 (IGF-1) and vascular endothelial growth ...
Abe, Nobuhiro +9 more
core +1 more source
Collapse of the femoral head is the most significant pathogenic complication arising from osteonecrosis of the femoral head. It is related to the disruption of the maintenance of cartilage and bone, and results in an impaired function of the vascular ...
Leilei Chen +6 more
doaj +1 more source
A Rabbit Model of Avascular Necrosis of Femoral Head Using Surgical Trauma and Systemic Steroids
Objective:Avascular necrosis of the femoral head (ANFH) is a disease caused by the diminished circulation of the femoral head. The incidence of the disease is increasing and it has heavy socioeconomical burden.
Hakan ÖZBEN
doaj +1 more source
Osteonecrosis becomes a more widespread problem as the population is getting older. Current osteonecrosis diagnosis not only requires invasive procedures but also often leads to surgical replacement.
D. Wang +6 more
doaj +1 more source
Osteonecrosis of the femoral head, an intractable but common disease that eventually triggers collapse of the femoral head, is characterized by increased osteoclast activity and markedly decreased osteoblast activity in the necrotic region of the femoral
Cheng Wang +17 more
doaj +1 more source
Dose-dependent new bone formation by extracorporeal shock wave application on the intact femur of rabbits [PDF]
Background: Whereas various molecular working mechanisms of shock waves have been demonstrated, no study has assessed in detail the influence of varying energy flux densities (EFD) on new bone formation in vivo. Methods: Thirty Chinchilla bastard rabbits
Hausdorf, J. +6 more
core +1 more source
Objective To evaluate the overall diagnostic value related to magnetic resonance imaging (MRI) in patients with early osteonecrosis of the femoral head. Methods By searching multiple databases and sources, including PubMed, Cochrane, and Embase database,
Ya-Zhou Zhang +6 more
doaj +1 more source
Skeletal immaturity, rostral sparing, and disparate hip morphologies as biomechanical causes for Legg-Calvé-Perthes’ disease [PDF]
Legg-Calvé-Perthes' (Perthes') disease is a developmental disease of the hip joint that may result in numerous short and long term problems. The etiology of the disease remains largely unknown, but the mechanism is believed to be vascular and/or ...
Acheson +191 more
core +1 more source
Hip preserving surgery with concentrated autologous bone marrow aspirate transplantation for the treatment of asymptomatic osteonecrosis of the femoral head: retrospective review of clinical and radiological outcomes at 6 years postoperatively [PDF]
BackgroundWe had previously established concentrated autologous bone marrow aspirate transplantation (CABMAT), a one-step, low-invasive, joint-preserving surgical technique for treating osteonecrosis of the femoral head (ONFH). The present study aimed to
Akaogi Hiroshi +8 more
core +2 more sources

