Abstract Purpose To evaluate osteoarthritis (OA) progression across functional knee phenotypes (FKPs) over a follow‐up period of ≥10 years. Methods This retrospective longitudinal study included 388 patients (764 knees) with healthy knees or early OA (Kellgren–Lawrence grade ≤1) at baseline and a minimum follow‐up of 10 years.
Sang Jun Song +2 more
wiley +1 more source
Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi +5 more
wiley +1 more source
Bone marrow edema and subchondral fracture in osteonecrosis of the femoral head: analysis with MRI and CT [PDF]
Purpose: To study the relationship between bone marrow edema (BME) and subchondral fracture in osteonecrosis of the femoral head (ONFH), and to analyze MRI findings of subchondral fracture and correlate them with those of CT. Materials and Methods: Fifty
Abumis, Hesham M +2 more
core
Aims: The localization of necrotic areas has been reported to impact the prognosis and treatment strategy for osteonecrosis of the femoral head (ONFH).
Masanori Nishi +7 more
doaj +1 more source
Progress in bone tissue engineering biomaterials: Development, challenges, and prospects
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang +7 more
wiley +1 more source
Osteonecrosis of the femoral head due to brucellosis: a case report
Background Brucellosis is a zoonotic infection transmitted from infected animals to humans, osteonecrosis of the femoral head (ONFH) is a devastating disease that affects patients’ life with pain, dysfunction of walking and always lead to total hip ...
Peixu Wang +3 more
doaj +1 more source
Hypoxia-inducible factor prolyl hydroxylase inhibitor prevents steroid-associated osteonecrosis of the femoral head in rabbits by promoting angiogenesis and inhibiting apoptosis. [PDF]
The purpose of this study was to investigate the preventive effect of ethyl 3,4-dihydroxybenzoate(EDHB) on steroid-associated femoral head osteonecrosis(ONFH) in a rabbit model.
Lihong Fan +4 more
doaj +1 more source
Scintigraphic assessment of bone status at one year following hip resurfacing : comparison of two surgical approaches using SPECT-CT scan [PDF]
Objectives: To study the vascularity and bone metabolism of the femoral head/neck following hip resurfacing arthroplasty, and to use these results to compare the posterior and the trochanteric-flip approaches.
Costa, Matthew L. +6 more
core +1 more source
Early lesions of the labrum and acetabular cartilage in osteonecrosis of the femoral head
Osteonecrosis of the femoral head can be caused by a variety of disorders and affects the relatively young patient. Most studies have concentrated on the femoral changes; the sites of early lesions of the labrum and acetabular cartilage have not been ...
M. Leunig, R. Ganz, P. Kloen
core +2 more sources
Background Several methods are available for the treatment of early-stage osteonecrosis of the femoral head. Core decompression with implantation is a widely-used treatment.
Liangta Huang +9 more
doaj +1 more source

