Results 71 to 80 of about 177,090,840 (213)

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Treatment Trade‐Offs and Choices for Femoral Fractures: A Systematic Review and Meta‐Analysis

Orthopaedic Surgery, Volume 17, Issue 5, Page 1298-1313, May 2025.
This review examines the trade‐offs between surgical intervention and traction therapy for adult and elderly patients with femoral fractures and surgical contraindications, particularly in resource‐limited settings. While intramedullary nailing may offer better clinical outcomes, traction therapy is often preferred due to limited surgical resources ...
Jiarui Li, Zhu Guo, Tianrui Wang, Kunyue Xing, Wenzhuo Wang, Yaowei Liu, Jiyao Xing, Hongfei Xiang, Jingdong Wang, Bohua Chen, Dongming Xing, Xiaolin Wu   +11 more
wiley   +1 more source

Significance of Lateral Pillar in Osteonecrosis of Femoral Head: A Finite Element Analysis

Chinese Medical Journal, 2017
Background: The lateral pillar of the femoral head is an important site for disease development such as osteonecrosis of the femoral head. The femoral head consists of medial, central, and lateral pillars.
Peng-Fei Wen, Wan-Shou Guo, Qi-Dong Zhang, Fu-Qiang Gao, Ju-An Yue, Zhao-Hui Liu, Li-Ming Cheng, Zi-Rong Li   +7 more
doaj   +1 more source

A Criterion of Reduction Quality of Femoral Neck Fractures Based on Spatial Residual Displacements of Femoral Head

Orthopaedic Surgery, Volume 17, Issue 5, Page 1503-1512, May 2025.
The new reduction criterion of reduction quality was based on two indicators of residual displacements: the postoperative residual displacement of the center of the femoral head and the postoperative residual rotational displacement. When the postoperative residual displacement of the center of the femoral head is ≤ 10.22 mm, and the postoperative ...
Shuang‐Shuang Cui, Li‐Kun Zhao, Jing‐Bo Yu, Jian‐Xiong Ma, Xin‐Long Ma   +4 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Frequency of Human Brucellosis Complications in West Asia: A Systematic Review and Meta‐Analysis

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
In 51.66% of the included studies in West Asia, the sample size was inadequate for at least half of the complications measured. ABSTRACT Background Brucellosis is a multi‐systemic zoonotic infection. The West Asia/Middle East region is an important global hotspot for brucellosis.
Aliasghar Fakhri‐Demeshghieh, Elnaz Rostamzaman, Fatemeh Sayareh, Amir Nikoukar, Faranak Farahani, Farniya Bakhtiary nia, Helia Sepahvand, Maryam Khaleghi, Mohammadsaeed Azamian, Mohammad Reza Shirzadi, Hesameddin Akbarein, Vahid Rahmanian   +11 more
wiley   +1 more source

Is There a Difference in Occurrence of Complications Between Adults With Hemoglobin SS and Hemoglobin SC Disease: An Extended Systematic Review

European Journal of Haematology, Volume 117, Issue 4, Page 824-837, October 2026.
ABSTRACT Sickle cell disease (SCD) is characterized by both acute and chronic complications. The clinical manifestation of these complications differs between genotypes. Given the large amount of research already published, this systematic review aims to offer a complete overview of types of sickle cell complications between adults in the most common ...
Martijn van der Meer, Kim Velsink, Wing H. Tong, Jan W. Schoones   +3 more
wiley   +1 more source

Fracture Risk Associated With Long‐Term Discontinuation of Postmenopausal Osteoporosis Treatment: A French Population‐Based Study Using National Claims Data (Système National des Données de Santé)

ACR Open Rheumatology, Volume 8, Issue 9, September 2026.
Objective This retrospective cohort study evaluated the long‐term discontinuation (LTD) of osteoporosis treatments in postmenopausal women in France and associated fracture risk and economic burden. Methods From the national French health care database (Système National des Données de Santé), we included postmenopausal women aged ≥60 years initiating ...
Audrey Lajoinie, Meriem Benmerad, Magali Laborey, Pascale Samama, Gaëlle Désaméricq, Leila Chelbani, Karine Briot   +6 more
wiley   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, Volume 13, Issue 49, 3 September 2026.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Effects of hyperbaric oxygen and inducible nitric oxide synthase inhibitor treatment on femoral head osteonecrosis in a rat model [PDF]

, 2013
Introduction: Apoptosis is the final destiny of many cells in the body, though this process has been observed in some pathological processes. One of these pathological processes is femoral head non-traumatic osteonecrosis.
Kalhor, Ali
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