Results 81 to 90 of about 22,149 (272)

Leveraging extracellular vesicle biology for novel tests and therapeutics for kidney fibrosis

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Extracellular vesicles (EVs) are bilipid membrane‐encased nanoparticles that play critical roles as cell‐to‐cell messengers and waste management mechanisms. EVs cargos can be leveraged as biomarkers to develop minimally invasive tests for kidney fibrosis and guide personalised mechanism‐driven care.
Chin‐Ya Sophie Chiang, Andrew J. Kassianos, Helen Grania Healy, Monica Suet Ying Ng   +3 more
wiley   +1 more source

Ceramic-on-ceramic bearings in hip arthroplasty STATE OF THE ART AND THE FUTURE

, 2012
02.05.13 KB.
Bragdon CR, Furuya K, Millar NL, Mittelmeier H, Nizard RS, Park YS, Riska EB, Salzer M, Sariali E, Vendittoli P, Wagner H, Winter M   +11 more
core   +1 more source

Medial closing wedge distal femoral varus osteotomy alters the stress distribution pattern of the patellofemoral joint: An evaluation using computed tomography osteoabsorptiometry

Journal of Experimental Orthopaedics, Volume 13, Issue 2, April 2026.
Abstract Purpose This study aimed to (1) assess changes in subchondral bone density distribution across patellofemoral (PF) joint before and after medial closing wedge‐distal femoral varus osteotomy (MCW‐DFVO) and (2) determine correlation between PF alignment and changes in bone density distribution.
Masanari Hamasaki, Eiji Kondo, Koji Iwasaki, Yuki Suzuki, Masatake Matsuoka, Tomohiro Onodera, Daisuke Momma, Masayuki Inoue, Kazunori Yasuda, Tomonori Yagi, Norimasa Iwasaki   +10 more
wiley   +1 more source

Romosozumab Versus Teriparatide for the Treatment of Postmenopausal Osteoporosis: An Overview of Systematic Reviews With Direct and Indirect Meta‐Analyses

International Journal of Rheumatic Diseases, Volume 29, Issue 4, April 2026.
ABSTRACT Aim To summarize the evidence of efficacy and safety of romosozumab compared to teriparatide for postmenopausal osteoporosis. Methods A literature search was performed in Medline, the Cochrane Library, CRD, and LILACS until November 2023. We included systematic reviews with meta‐analyses on the use of romosozumab compared to teriparatide in ...
Tayna Felicissimo Gomes de Souza Bandeira, Patricia Melo Aguiar, Cid Manso de Mello Vianna, Gabriela Bittencourt Gonzalez Mosegui, Tácio de Mendonça Lima   +4 more
wiley   +1 more source

SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts [PDF]

, 2017
Acknowledgements We sincerely thank the patients and family members who participated in this study. We would also like to thank Stefan Esher, Umeå University, for help with genealogy, and Anna Westerlund for excellent technical assistance.
Ameur, Adam, Coxon, Fraser P., Dahl, Niklas, Hallmans, Göran, Helfrich, Miep H., Henning, Petra, Kellgren, Therese G., Klar, Joakim, Lerner, Ulf H., Lönnerholm, Torsten, McDermott, Emma, Rydén, Patrik, Sandström, Per-Erik, Stattin, Eva-Lena, Stecksen-Blicks, Christina, Wikström, Johan   +15 more
core   +1 more source

Wine‐Processed Cornus officinalis Ameliorates Osteoarthritis via Modulating M1/M2 Macrophage Polarization

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Cornus officinalis (CO) is a traditional herbal medicine renowned in Traditional Chinese Medicine (TCM) for its properties of tonifying the liver and kidney and replenishing vital essence. Meanwhile, wine‐processed CO (pCO) exhibits superior pharmacological effects, including anti‐inflammatory, antioxidant and anti‐fibrotic activities. However,
Yongsheng Fu, Minghua Zhao, Xudong Huang, Yingchao Ren, Weiguo Wang   +4 more
wiley   +1 more source

Arthroscopic-Assisted Core Decompression for Osteonecrosis of the Femoral Head

Arthroscopy Techniques, 2014
The management of pre-collapse osteonecrosis of the femoral head is controversial. Core decompression is a technique that theoretically decreases the intraosseous pressure of the femoral head, resulting in a local vascularized healing response.
Anil K. Gupta, M.D., M.B.A., Rachel M. Frank, M.D., Joshua D. Harris, M.D., Frank McCormick, M.D., Richard C. Mather, M.D., Shane J. Nho, M.D., M.S.   +5 more
doaj   +1 more source

A Novel Long Noncoding RNA–LNC000133 Associated With Steroid‐Induced Osteonecrosis of the Femoral Head Promotes Osteoblast Differentiation Through Bone Marrow Mesenchymal Stem Cells‐Derived Exosomes Pathway: A Bioinformatics Validation and Detailed Mechanistic Study

Journal of Cellular and Molecular Medicine, Volume 30, Issue 8, April 2026.
ABSTRACT Steroid‐induced osteonecrosis of the femoral head (SONFH) is a debilitating disease caused by glucocorticoid abuse, characterized by complex pathogenesis and unclear molecular mechanisms. Dysfunction of bone marrow mesenchymal stem cells (BMSCs) and their exosome‐mediated signalling is a key contributor to SONFH, although the precise ...
Chengbin Yang, Tixiong Xia, Xi Li, Tong Chen, Yingxing Xu   +4 more
wiley   +1 more source

Etiopatogenia de la osteonecrosis idiopática de cadera: situación actual [PDF]

, 2009
Al margen de las numerosas hipótesis etiopatogénicas sobre la osteonecrosis atraumática de cadera, la fisiopatología de la enfermedad sigue siendo, en la actualidad, motivo de debate.
Escribá, I., Renovell Ferrer, Pablo, Silvestre Muñoz, Antonio   +2 more
core  

PTH[1-34] improves the effects of core decompression in early-stage steroid-associated osteonecrosis model by enhancing bone repair and revascularization [PDF]

, 2017
published_or_final_versio
Heng, BCA, Hu, B, Lin, T, Meng, J, Miao, D, Shen, W, Shen, Y, Shi, Z, Yan, S, Yang, X, Ye, C, Zhao, C, Zhou, C, Zhu, H   +13 more
core   +3 more sources