Objective Chondrocytemetabolic dysfunction plays an important role in osteoarthritis (OA) development during aging and obesity. Protein posttranslational modifications (PTMs) have recently emerged as an important regulator of cellular metabolism. We aim to study one type of PTM, lysine malonylation (MaK), and its regulator sirtuin 5 (Sirt5) in OA ...
Huanhuan Liu+11 more
wiley +1 more source
Osteopathic Manipulation in the Management of Chronic Pain: Current Perspectives
John C Licciardone,1 Matthew J Schultz,1 Brook Amen2 1Department of Family Medicine, University of North Texas Health Science Center, Fort Worth, TX, USA; 2Gibson D.
Licciardone JC, Schultz MJ, Amen B
doaj
“Princess and the pea” – an assessment tool for palpation skills in postgraduate education
Background In osteopathic medicine, palpation is considered to be the key skill to be acquired during training. Whether palpation skills are adequately acquired during undergraduate or postgraduate training is difficult to assess.
Rainer Kamp+2 more
doaj +1 more source
Medicinal Boxes Recognition on a Deep Transfer Learning Augmented Reality Mobile Application [PDF]
Taking medicines is a fundamental aspect to cure illnesses. However, studies have shown that it can be hard for patients to remember the correct posology. More aggravating, a wrong dosage generally causes the disease to worsen. Although, all relevant instructions for a medicine are summarized in the corresponding patient information leaflet, the latter
arxiv
Podcasts in health education—Insights from a scoping review and survey
Abstract Podcasts have rapidly emerged as a powerful tool for health communication, especially since the COVID‐19 pandemic. While evidence shows that podcasts can enhance student knowledge, confidence, and flexibility in learning, their educational impact is primarily studied within formal academic contexts.
Matthew J. Barton+2 more
wiley +1 more source
Ethics for Digital Medicine: A Path for Ethical Emerging Medical IoT Design [PDF]
The dawn of the digital medicine era, ushered in by increasingly powerful embedded systems and Internet of Things (IoT) computing devices, is creating new therapies and biomedical solutions that promise to positively transform our quality of life. However, the digital medicine revolution also creates unforeseen and complex ethical, regulatory, and ...
arxiv
Behavioral health training for integrated behavioral health: A Delphi study
Abstract Using a classical Delphi design, the authors used an interdisciplinary panel of behavioral health experts in integrated behavioral health (IBH) to identify foundational skills and knowledge counselor educators need to teach clinical mental health counselors for IBH practice. Eighty‐eight statements were identified.
Nicholas Schmoyer+3 more
wiley +1 more source
Integrative AI-Driven Strategies for Advancing Precision Medicine in Infectious Diseases and Beyond: A Novel Multidisciplinary Approach [PDF]
Precision medicine, tailored to individual patients based on their genetics, environment, and lifestyle, shows promise in managing complex diseases like infections. Integrating artificial intelligence (AI) into precision medicine can revolutionize disease management.
arxiv
Evaluation of CYP2C19 Clinical Decision Support Alerts to Guide P2Y12 Inhibitor Prescribing
P2Y12 inhibitor selection involves numerous factors, including CYP2C19 genetics, since evidence demonstrates reduced clopidogrel efficacy in patients with decreased or no function CYP2C19 variants. In 2020, Indiana University health embedded interruptive clinical decision support (CDS) alerts in the electronic health record (EHR) to recommend ...
Ashley N. Springer+14 more
wiley +1 more source
Investigation Toward The Economic Feasibility of Personalized Medicine For Healthcare Service Providers: The Case of Bladder Cancer [PDF]
In today's complex healthcare landscape, the pursuit of delivering optimal patient care while navigating intricate economic dynamics poses a significant challenge for healthcare service providers (HSPs). In this already complex dynamics, the emergence of clinically promising personalized medicine based treatment aims to revolutionize medicine.
arxiv