Results 121 to 130 of about 75,261 (235)

Serum Uric Acid Levels in Older Adults: Associations With Clinical Outcomes and Implications for Reference Intervals in Those Aged 70 Years and Over

open access: yesArthritis Care &Research, Volume 78, Issue 3, Page 407-416, March 2026.
Objective Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged ≥70 years old.
Amanda J. Rickard   +15 more
wiley   +1 more source

Adipokines and Associations With Incident Osteoporotic Fracture in Patients With Rheumatoid Arthritis

open access: yesArthritis Care &Research, Volume 78, Issue 3, Page 316-324, March 2026.
Objective We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, and fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker   +9 more
wiley   +1 more source

The triangular relationship of serum uric acid, osteoporosis or osteopenia, and body mass index for men and postmenopausal women

open access: yesScientific Reports
Osteoporosis (OP) is a systemic bone disease characterized by reduced bone density and quality, leading to increased bone fragility and a higher risk of fractures.
Ziran Xiu, Zhengnan Gao, Lan Luo
doaj   +1 more source

Association between C-reactive protein-triglyceride glucose index and abnormal BMD in middle-aged and elderly patients with type 2 diabetes mellitus: a cross-sectional study

open access: yesFrontiers in Medicine
Background and aimsBone loss is an irreversible physiological change occurring with age. Type 2 diabetes mellitus (T2DM) is associated with poor bone health, and insulin resistance (IR) and inflammation are common pathologic mechanisms in T2DM and ...
Yuan Zhang, Yali Jing
doaj   +1 more source

CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
CGRP interacts with HMEC‐1 by binding to surface receptors, influencing the downstream FAK/AKT/VEGF signaling pathway, and promoting the secretion of ANGPTL4 from vascular endothelial cells into the bone microenvironment. This, in turn, regulates the differentiation of BMSCs into osteoblasts, thus promoting bone formation. ABSTRACT Bone angiogenesis is
Qiong Lu   +9 more
wiley   +1 more source

Radiographic Assessment of Spinal Degeneration in Vervet Monkeys (Chlorocebus aethiops): Prevalence, Patterns, and Relevance to Primate Aging Models

open access: yesAmerican Journal of Primatology, Volume 88, Issue 3, March 2026.
Radiographic evaluation of 70 vervet monkeys (Chlorocebus aethiops) maintained under human care revealed a high prevalence of age‐related spinal degeneration. Osteophytes emerged earliest and most prominently in the lumbar region. These region‐specific patterns parallel those reported in other catarrhine primates, supporting C.
Camille Gabriela Ramos Portal   +7 more
wiley   +1 more source

Relationship of lumbar vertebral volumetric bone mineral density with trunk muscle density assessed by quantitative computed tomography in maintenance hemodialysis patients

open access: yesRenal Failure
Background Sarcopenia due to abnormal muscle metabolism and osteoporosis due to abnormal bone metabolism are common complications in maintenance hemodialysis (MHD) patients. The aim of this study was to investigate the association between volumetric bone
Lijiao Yang   +5 more
doaj   +1 more source

Tuberculosis Presenting as Migratory Arthritis: A Case Report from Iraq

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Extrapulmonary tuberculosis is uncommon, and musculoskeletal involvement presenting as migratory arthritis is particularly rare in immunocompetent individuals, often leading to misdiagnosis and delayed treatment. We report the case of a 66‐year‐old man with diabetes mellitus who presented with recurrent migratory inflammatory arthritis ...
Farah Jaafar Mahdi   +7 more
wiley   +1 more source

Replacement of leisure-time sedentary behavior with various physical activities and the risk of osteopenia and osteoporosis: evidence from the UK Biobank

open access: yesJournal of Exercise Science & Fitness
Objective: Associations between sedentary behavior (SB) during leisure time and the risk of osteopenia and osteoporosis are inconclusive. We aimed to examine the impact of replacing sedentary time with equivalent durations of various physical activities ...
Zhuoyao Tian   +12 more
doaj   +1 more source

Untargeted Proteomics Profiling of Liver and Plasma in Fed and Fasted Liver‐Specific Glycogen Storage Disease Type Ia (GSD Ia) Mice: Toward Potential Protein Biomarkers

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Glycogen storage disease type Ia (GSD Ia) is a rare autosomal recessive inherited disorder of carbohydrate metabolism, caused by a deficiency in glucose 6‐phosphatase‐α (G6PC1). Patients primarily suffer from failure to thrive, hepatomegaly, and severe fasting intolerance, biochemically characterized by hypoketotic, hypoglycemia, and ...
Ruiqi Xiao   +7 more
wiley   +1 more source

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