Results 141 to 150 of about 75,261 (235)

MECP2 Insufficiency Attenuates RUNX2‐Dependent Osteoblast Differentiation via miR‐126‐3p/DKK1‐Mediated Canonical Wnt Signaling Inhibition in Rett Syndrome

open access: yesThe FASEB Journal, Volume 40, Issue 4, 28 February 2026.
MECP2 insufficiency leads to upregulation of miR‐126‐3p, which in turn enhances the endogenous Wnt antagonist DKK1. DKK1 inhibits the canonical Wnt signaling pathway, thereby impairing RUNX2‐dependent osteoblast differentiation. ABSTRACT Rett syndrome (RTT) is a rare neurodevelopmental disorder caused by loss‐of‐function mutations in the gene encoding ...
Shuangshan Dong   +12 more
wiley   +1 more source

Aging‐Driven Inter‐Organ Crosstalk in Postmenopausal Osteoporosis: From Immunometabolic Drift to Multisystem Frailty

open access: yesThe FASEB Journal, Volume 40, Issue 4, 28 February 2026.
Postmenopausal osteoporosis (PMOP) is increasingly recognized as an aging‐associated, multisystem state of fragility, in which estrogen deficiency exacerbates immune and metabolic drift across the bone marrow, skeletal muscle, adipose tissue, gut, vascular system, and neural circuits.
Xianlin Rao, Xiaoyu Cai
wiley   +1 more source

Osteopenia

open access: yes, 2018
Francis Deng   +2 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy