Results 71 to 80 of about 40,701 (228)

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source

The association between the AST/ALT ratio and osteopenia or osteoporosis in patients with type 2 diabetes mellitus

Endocrine Connections
Introduction: The aim of this study was to investigate the relationship between the AST/ALT ratio and osteopenia or osteoporosis in patients with type 2 diabetes mellitus (T2DM).
Yuan Zhang, Guanhua Chen, Shanshan Lv, Weimin Wang, Yali Jing   +4 more
doaj   +1 more source

Bone Health and Aging in Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Klinefelter syndrome (KS) is typically diagnosed in young adults, but advances in prenatal testing have led to its recognition at a much earlier age. Conversely, diagnosis in late adulthood remains uncommon, but still occurs. Independently from the age at diagnosis, KS individuals now receive more accurate and tailored care management than in ...
Filippo Vignali, Daniele Renda Livraghi, Francesco Costantino, Sara De Vincentis, Vincenzo Rochira   +4 more
wiley   +1 more source

Multidimensional Determinants of Quality of Life in Men With Klinefelter Syndrome: A Narrative Review of Workshop Evidence

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS), typically characterized by a 47, XXY karyotype, is the most common sex chromosomal aneuploidy in males, with a prevalence of approximately one in 600–660 individuals. Despite its frequency, the syndrome remains significantly underdiagnosed, with 50%–75% of affected individuals never receiving a clinical ...
Francesca Allosso, Lucia Digitale Selvaggio, Daniela Pasquali   +2 more
wiley   +1 more source

Association between thyroid function and osteopenia or osteoporosis: a cross-sectional study in China

Scientific Reports
Thyroid dysfunction is associated with bone health, but the relationship with osteopenia remains unclear. This study aimed to investigate the association between thyroid function and osteopenia/osteoporosis across different age groups. The study included
Ling Zhang, Chao Ma, Xin Yin, Fenglian Zhang, Xiuyan Fang, Chen Zhang, Lei Shang, Li Ma   +7 more
doaj   +1 more source

Factors Affecting Surgical Outcomes Following Rotationplasty in Paediatric Sarcoma: A Literature Review

ANZ Journal of Surgery, EarlyView.
Rotationplasty is a durable limb‐salvage option for paediatric lower‐limb sarcoma. Across 58 studies and 1,217 patients, long‐term functional, psychosocial, and quality‐of‐life outcomes were favourable, often surpassing amputation and endoprosthetic reconstruction.
Rachel H. Ko, Stewart Morrison, Daniel J. Wilks   +2 more
wiley   +1 more source

Assessment of the Relationship Between Bone Mineral Density and Disease Activity in Ankylosing Spondylitis Patients with Osteopenia

Türk Osteoporoz Dergisi, 2013
Summary Aim: Ankylosing Spondylitis (AS) is a chronic inflammatory disease. Spinal osteopenia is common in AS, probably due to immobility and local cytokine release.
Hayal Güler, Nilgün Üstün, Veli Enes Bolaç, Abdullah Erman Yağız, Ayhan Mansuroğlu, Erhan Yengil, Ayşe Dicle Turhanoğlu   +6 more
doaj   +1 more source

Developmental Osteopenia: An Explanation for Fractures in Young Infants

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim is to test whether a fraction of full‐term infants pass through a phase of postnatal fracture susceptibility and whether this physiological phase explains real‐world fracture age distributions in young infants. Methods Preterm infant data were used to establish fracture risk zones based on bone quality (using Speed of Sound, SOS ...
Chris Brook, Julie Mack, Waney Squier
wiley   +1 more source

Comorbid conditions after allogeneic haematopoietic stem cell transplantation in young adults in Germany—A prospective, multicentre trial

British Journal of Haematology, EarlyView.
Summary Young adults (YA) are particularly affected by comorbid conditions following allogeneic haematopoietic stem cell transplantation (alloHSCT), as they have to live with them for many years. This is the first multicentre prospective study investigating sequelae after alloHSCT in YA in Germany. In total, 107 patients who survived relapse‐free until
Pauline Rocke, Lena Tandetzky, Daniel Wolff, Katharina Egger‐Heidrich, Daniela Heidenreich, Kerstin Schaefer‐Eckart, Eva Wagner‐Drouet, Jochen J. Frietsch, Andreas Hochhaus, Inken Hilgendorf   +9 more
wiley   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source