Results 101 to 110 of about 291,165 (296)
Optical Windows for Transcranial Brain Imaging in Living Mice: Skull Thinning, Clearing, and Beyond
Advanced Science, EarlyView.Longitudinal, noninvasive in vivo imaging is crucial for studying brain physiology. Advances in transcranial optical windows and multiphoton microscopy have improved imaging depth, but their performance often deteriorates over time. This work investigated various transcranial window approaches and found that skull regrowth limits image quality.
Yiming Fu +5 more
wiley +1 more source
Hand fracture epidemiology and etiology in children—time trends in Malmö, Sweden, during six decades
Journal of Orthopaedic Surgery and Research, 2019 Background The aim of this study was to describe hand fracture epidemiology/etiology in city children and describe time trend during six decades. Patients and methods A single hospital serves the entire city population of 271,271 (year 2005). Through the
Vasileios Lempesis +4 more
doaj +1 more source
Advanced Science, EarlyView.An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang +10 more
wiley +1 more source
Advanced Science, EarlyView.A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang +12 more
wiley +1 more source
Male Osteoporosis in Our Population [PDF]
, 2002 Male osteoporosis is encountered as an important problem in clinical medicine in the recent years. Our purpose was to evaluate bone mineral density (BMD) of vertebrae (L2-L4) and femur (neck and Wards) distributed according to age groups in males who ...
Seher Kocaoğlu +3 more
core
Vitamin D Levels in Patients with Osteoporosis [PDF]
, 2011 Aim: In this study, we aimed to determine vitamin D levels and related parameters of patients referring to our osteoporosis follow-up clinic. Material and Methods: Age, gender, occupation, education level, menopausal state, menopause age and vitamin D ...
İsmail Cömertoğlu +4 more
core +1 more source
Advanced Science, EarlyView.In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang +19 more
wiley +1 more source
The Effect of Alendronate in Male Osteoporosis [PDF]
, 2004 Osteoporosis in men is increasingly recognized as an important public health issue because of mortality and disability. Approximately 25-30% of all hip fractures occur in men and men are over 3 times more likely to die following a hip fracture than women.
Ebru Şahin +8 more
core
Advanced Science, EarlyView.GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han +16 more
wiley +1 more source
Orthopaedic Surgery, 2019 Objectives To investigate the knowledge and practices of Chinese doctors in the management of osteoporotic fractures after the Chinese osteoporotic fracture guidelines update and aseries of medical education in 2017.
Jin Lu +4 more
doaj +1 more source