Results 121 to 130 of about 266,825 (311)

Visualizing Turner Syndrome

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Turner syndrome (TS) continues to present a diagnostic challenge to healthcare professionals. The diagnostic challenges associated with TS result in delayed treatment and clinical care. Here we provide an update of the physical appearance of girls and women with TS by presenting clinical photographs and detailed clinical descriptions of 25 ...
Kirstine Stochholm   +2 more
wiley   +1 more source

The Synthesis of Nonsymmetric α‐hydroxy‐ethylidenebisphosphonic Derivatives by the Pudovik Reaction, Their Reactions, and Cytotoxic Activity

open access: yesAsian Journal of Organic Chemistry, EarlyView.
Nonsymmetric α‐hydroxy‐ethylidenebisphosphonates (HEBPs) are synthesized by the Pudovik reaction of dialkyl α‐oxo‐ethylphosphonates and P‐reagents (such as dialkyl phosphites, alkyl phenyl‐H‐phosphinates or diarylphosphine oxides). In the presence of 40% diethylamine, the primary adducts rearrange to the corresponding phosphonoyl‐phosphonate and ...
Zsuzsanna Szalai   +8 more
wiley   +1 more source

Clinical–Radiological Spectrum of Cerebral Amyloid Angiopathy‐Related Inflammation

open access: yesAnnals of Neurology, EarlyView.
Objective To identify clinical and radiological features of cerebral amyloid angiopathy‐related inflammation (CAA‐ri), and compare these features with those of sporadic CAA, to improve the understanding, diagnosis, and clinical care of CAA‐ri. Methods We retrospectively reviewed routine clinical data from 37 patients with CAA‐ri and 158 patients with ...
Larysa Panteleienko   +9 more
wiley   +1 more source

Irisin‐Loaded Dissolving Microneedles Promote Rapid Wound Healing

open access: yesAdvanced NanoBiomed Research, EarlyView.
Schematic of effective wound healing facilitated by water‐degradable microneedles loaded with irisin that enhance irisin penetration, fibroblast migration, differentiation, and extracellular matrix synthesis at the wound site. Irisin, an exercise‐induced myokine with anti‐inflammatory and regenerative activity, is incorporated into dissolving poly ...
Yu‐Chi Pan   +6 more
wiley   +1 more source

GLYCEROIURIA, PSYCHOMOTOR RETARDATION, SPASTICITY DYSTROPHIC MYOPATHY, AND OSTEOPOROSIS IN A SIBSHIP [PDF]

open access: bronze, 1977
Edward R.B. McCabe   +5 more
openalex   +1 more source

Peptide/Antibody–Drug Conjugates for Therapeutic Applications in Inflammatory Disease

open access: yesAdvanced NanoBiomed Research, EarlyView.
Peptide/antibody–drug conjugates (PADCs) combine ligand specificity and cleavable linkers to deliver drugs precisely to disease sites with minimal toxicity. While current approvals focus on oncology, this review examines their untapped potential in inflammatory diseases, detailing mechanisms of targeted delivery and highlighting advances that position ...
Yeongji Jang   +5 more
wiley   +1 more source

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