Results 161 to 170 of about 673,953 (357)

Decision letter for "The Impact of Various Anti‐Osteoporosis Drugs on All‐Cause Mortality After Hip Fractures: A Nationwide Population Study"

, 2022

openalex   +1 more source

Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis.

New England Journal of Medicine, 2001
R. Neer, C. Arnaud, J. Zanchetta, R. Prince, G. Gaich, J. Reginster, A. Hodsman, E. Eriksen, S. Ish-shalom, H. Genant, O. Wang, B. Mitlak   +11 more
semanticscholar   +1 more source

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

Advanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang, Qi Gao, Yi Peng, Huan Zhang, Qi Shen, Meihong Guo, Yuqing Gong, Lei Chu, Weidong Wu, Yanting Wen, Wangsen Cao, Yong Wang, Lihui Wang   +12 more
wiley   +1 more source

Lactobacillus Salivarius‐Derived Indole‐3‐Acetic Acid Promotes AHR‐PARP1 Axis‐Mediated DNA Repair to Mitigate Intestinal Aging

Advanced Science, EarlyView.
Indole‐3‐acetic acid (IAA) acting as one of the aryl hydrocarbon receptor (AHR) endogenous ligands is identified to be derived from Lactobacillus salivarius via its catalytic enzyme (ALDH) rather than host cells. Lactobacillus salivarius and IAA supplementation effectively mitigate intestinal aging by facilitating AHR‐poly (ADP‐ribose) polymerase 1 ...
Zheng Cao, Cui Zhang, Hehua Lei, Weichuan Lin, Wenkai Yu, Xin Gao, Yanmeng He, Xinzhi Li, Qingwei Xiang, Zhiwen Zhang, Weifei Luo, Andrew D. Patterson, Limin Zhang, Gang Chen   +13 more
wiley   +1 more source

Impact of patient education by nurse case managers on decision making for out-of-pocket anti-osteoporotic pharmaceutical therapy: a single-center retrospective study

BMC Nursing
Background Osteoporosis is a common condition that increases the risk of fracture and mortality. In Taiwan, clinical guidelines recommend pharmaceutical therapy for patients with a T-score of ≤ − 2.5; however, Taiwan’s National Health Insurance (NHI ...
Ya-Lian Deng, Hsu-Tung Lee, Shih-Yi Lin, Tan-Hsiu Liao, Chia-Tien Hsu   +4 more
doaj   +1 more source

Incidence and Economic Burden of Osteoporosis‐Related Fractures in the United States, 2005–2025

Journal of Bone and Mineral Research, 2007
R. Burge, B. Dawson-Hughes, D. Solomon, J. Wong, Alison B King, A. Tosteson   +5 more
semanticscholar   +1 more source

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

Advanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang, Xiaohui Tao, Ning Zhang, Xin Yang, Hewen Jiang, Xiaofei Li, Shenghang Wang, Shijian Ding, Sifan Yu, Huarui Zhang, Yihao Zhang, Nanxi Li, Haitian Li, Zhanghao Li, Xiaoxin Wen, Meiheng Sun, Chuanxin Zhong, Jin Liu, Yuanyuan Yu, Xianghang Luo, Tao Zhang, Shu Zhang, Péter Ferdinandy, Yu Huang, Daqing Ma, Aiping Lu, Baoting Zhang, Ge Zhang   +27 more
wiley   +1 more source

A profiling analysis of contributions of cigarette smoking, dietary calcium intakes, and physical activity to fragility fracture in the elderly [PDF]

, 2018
Fragility fracture and bone mineral density (BMD) are influenced by common and modifiable lifestyle factors. In this study, we sought to define the contribution of lifestyle factors to fracture risk by using a profiling approach.
Center, Jacqueline R, Dutkiewicz, Eryk, Eisman, John A, Nguyen, Diep N, Nguyen, Tuan V, Pham, Thuy T   +5 more
core   +1 more source

FETUINA-A IN DIAGNOSTICS OF OSTEOPOROSIS IN PATIENTS WITH RHEUMATOID ARTHRITIS

, 2019
E. Papichev, B. V. Zavodovsky, L. Seewordova, Y. Akhverdyan, Yu. V. Polyakova, I.А. Zborovskaya   +5 more
openalex   +1 more source

Risk Factors for Ten-Year Risk of Osteoporosis in Type 2 DM Patients Attending Tikur Anbessa Specialized Hospital Diabetic Center Cross-sectional Study [PDF]

Gebeyehu Tessema Azibte, Theodros Aberra, Zekarias Seifu Ayalew, Kibrekidusan Aynekulu Tsige, Bereket Abraha Molla, Mahlet Tsige Weldeamanuel, Waltengus Birhanu, Biruk Abate Legesse   +7 more
openalex   +1 more source