Results 161 to 170 of about 634,680 (384)

Selection of DNA Aptamers Against Parathyroid Hormone for Electrochemical Impedimetric Biosensor System Development

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT This work presents the pioneering development of an aptamer‐based electrochemical biosensor for real‐time monitoring of parathyroid hormone (PTH) levels, with a focus on intraoperative assessment during parathyroid surgery. It introduces, for the first time, the selection and characterization of aptamers targeting distinct segments of the PTH ...
Reza Didarian   +5 more
wiley   +1 more source

Romosozumab for the treatment of osteoporosis

open access: yesOsteoporosis and Sarcopenia, 2018
Romosozumab, a specific inhibitor of sclerostin, is a unique approach to therapy for postmenopausal osteoporosis and related disorders. The elucidation of sclerostin deficiency as the molecular defect of syndromes of high bone mass with normal quality ...
Michael R. McClung
doaj  

Novel Sulfonylhydrazones With Sulfonate Ester Framework: Promising Dual Inhibitors of AChE and hCAs

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of individuals worldwide. Treatment strategies for AD vary depending on cognitive and behavioral symptoms, with cholinergic replacement therapy using acetylcholinesterase (AChE) inhibitors being one of the primary approaches.
Cansu Öztürk   +3 more
wiley   +1 more source

Screening, prevention and management of osteoporosis among Canadian adults

open access: yesHealth Promotion and Chronic Disease Prevention in Canada, 2018
Introduction: This study provides a benchmark for the nationwide use of osteoporosis screening, prevention and management strategies among Canadians aged 40 years and older (40+) using data collected one year prior to the release of Osteoporosis Canada’s
Siobhan O’Donnell   +1 more
doaj   +1 more source

Utilization and expenditure on medicines for the management of osteoporosis in Ireland: A repeated cross‐sectional study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Osteoporosis is a prevalent skeletal disease characterized by low bone mass and increased fracture risk. Management of osteoporosis typically involves antiresorptive and anabolic therapies, which are reimbursed in Ireland through various drug schemes.
Amelia Smith   +4 more
wiley   +1 more source

Periodontitis and the Elderly: An Overview of the Disease and its Impact on an Aging Population [PDF]

open access: yes, 2019
Periodontitis affects millions of Americans each year, and is especially prevalent among the elderly. Since periodontitis is a chronic, progressive condition, uninterrupted disease progression leads to irreversible oral damage; therefore, periodontitis ...
Weissenfluh, Nicole Grace
core   +1 more source

The role of different physical function tests for the prediction of fracture risk in older women

open access: yesJournal of Cachexia, Sarcopenia and Muscle
Background Physical function is an important risk factor for fracture. Previous studies found that different physical tests (e.g., one‐leg standing [OLS] and timed up and go [TUG]) predict fracture risk.
Giulia Gregori   +6 more
doaj   +1 more source

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