Results 41 to 50 of about 401,073 (266)

Vitamin D Receptor Gene Polymorphisms Modify Cardiometabolic Response to Vitamin D Supplementation in T2DM Patients

open access: yesScientific Reports, 2017
There is conflicting evidence on the favorable effects of vitamin D supplementation on metabolic profile in Type 2 diabetes mellitus (T2DM) patients and this might be due to genetic variations in vitamin D receptors (VDRs). Thus, we studied the metabolic
Nasser M. Al-Daghri   +8 more
doaj   +1 more source

Criteria for evaluating the effectiveness of osteoporosis treatment

open access: yesМедицинский совет, 2014
Currently, there are a number of effective drugs for the treatment of osteoporosis that increase bone mineral density and reduce the risk of fractures. However, till now there is no consensus of scientists on the optimal method of assessing response to ...
O. B. Ershova, A. V. Nazarova
doaj   +1 more source

Osteoporosis Prescreening using Panoramic Radiographs through a Deep Convolutional Neural Network with Attention Mechanism [PDF]

open access: yesarXiv, 2021
Objectives. The aim of this study was to investigate whether a deep convolutional neural network (CNN) with an attention module can detect osteoporosis on panoramic radiographs. Study Design. A dataset of 70 panoramic radiographs (PRs) from 70 different subjects of age between 49 to 60 was used, including 49 subjects with osteoporosis and 21 normal ...
arxiv  

Semi-Recumbent Vibration Exercise in Older Adults: A Pilot Study of Methodology, Feasibility, and Safety

open access: yesGerontology and Geriatric Medicine, 2019
Objectives: Older adults with impaired physical function are at risk for further functional decline in part due to limited ability to engage in regular exercise.
Murad H. Taani PhD, MPH, RN   +6 more
doaj   +1 more source

Osteoporosis in the European Union: medical management, epidemiology and economic burden

open access: yesArchives of Osteoporosis, 2013
SummaryThis report describes the epidemiology, burden, and treatment of osteoporosis in the 27 countries of the European Union (EU27).IntroductionOsteoporosis is characterized by reduced bone mass and disruption of bone architecture, resulting in ...
E. Hernlund   +9 more
semanticscholar   +1 more source

Phosphorylation of S122 in ERα is important for the skeletal response to estrogen treatment in male mice

open access: yesScientific Reports, 2022
Estrogen receptor alpha (ERα) signaling has beneficial skeletal effects in males. ERα signaling also affects other tissues, and to find bone-specific treatments, more knowledge regarding tissue-specific ERα signaling is needed.
Karin Horkeby   +9 more
doaj   +1 more source

An atlas of genetic influences on osteoporosis in humans and mice

open access: yesNature Genetics, 2018
Osteoporosis is a common aging-related disease diagnosed primarily using bone mineral density (BMD). We assessed genetic determinants of BMD as estimated by heel quantitative ultrasound in 426,824 individuals, identifying 518 genome-wide significant loci
John A. Morris   +83 more
semanticscholar   +1 more source

Osteoporosis in Men: A Review of an Underestimated Bone Condition

open access: yesInternational Journal of Molecular Sciences, 2021
Osteoporosis is called the ‘silent disease’ because, although it does not give significant symptoms when it is not complicated, can cause fragility fractures, with serious consequences and death.
G. Rinonapoli   +5 more
semanticscholar   +1 more source

Time trends in pediatric hand fracture incidence in Malmö, Sweden, 1950–2016

open access: yesJournal of Orthopaedic Surgery and Research, 2021
Background The hand is the second most fractured region in children. It is therefore important to update fracture epidemiology to be able to identify time trends for adequate health care planning. This study reports pediatric hand fracture incidence 2014–
Erika Bergman   +4 more
doaj   +1 more source

Multiscale modeling of cancellous bone considering full coupling of mechanical, electrical and magnetic effects [PDF]

open access: yesarXiv, 2021
Modeling of cancellous bone has important applications in the detection and treatment of fatigue fractures and diseases like osteoporosis. In this paper, we present a fully coupled multiscale approach considering mechanical, electrical and magnetic effects by using the multiscale finite element method and a two-phase material model on the microscale ...
arxiv  

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