Results 41 to 50 of about 427,163 (354)
Endocrine reviews, 2021 Osteoporosis is a global public health problem, with fractures contributing to significant morbidity and mortality. Although post-menopausal osteoporosis is most common, up to 30% of post-menopausal women, >50% of premenopausal women, and between 50-80 ...
P. Ebeling +5 more
semanticscholar +1 more source
Arthritis Care &Research, Accepted Article.Objective We evaluated the role of 25‐hydroxy vitamin D, prednisone and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25‐hydroxy vitamin D [25(OH)D] levels and other potential risk factors with BMD measures (spine T‐scores) and osteoporosis ...
Nima Madanchi +4 more
wiley +1 more source
In major joint diseases the human synovium retains its potential to form repair cartilage
Scientific Reports, 2023 The inner surface layer of human joints, the synovium, is a source of stem cells for the repair of articular cartilage defects. We investigated the potential of the normal human synovium to form novel cartilage and compared its chondrogenic capacity with
Ernst B. Hunziker +4 more
doaj +1 more source
Arthritis Care &Research, Accepted Article.Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo +19 more
wiley +1 more source
The Influence of Strontium on Bone Tissue Metabolism and Its Application in Osteoporosis Treatment
International Journal of Molecular Sciences, 2021 Osteoporosis is a chronic disease characterized by low bone mass caused by increased bone turnover and impaired bone microarchitecture. In treatment, we use antiresorptive or anabolic drugs, which usually have a unidirectional effect, i.e., they inhibit ...
Barbara Kołodziejska +2 more
semanticscholar +1 more source
Arthritis Care &Research, Accepted Article.Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren's disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr +5 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer +7 more
wiley +1 more source
Nursing Standard, 2006 Osteoporosis, as defined by the National Osteoporosis Foundation, is a disease that is characterized by low bone mass and structural deterioration of bone tissue, which leads to bone fragility and an increased susceptibility to fractures. Aging is only one factor that contributes to the development of osteoporosis.
Sambrook, P, Cooper, C
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The role of the P2X7 receptor on bone loss in a mouse model of inflammation-mediated osteoporosis
Bone Reports, 2017 In inflammatory autoimmune diseases, bone loss is frequent. In most cases, secondary osteoporosis is caused by treatment with systemic glucocorticoid. However, the pathogenesis behind the bone loss is presumed multifactorial.
T.M. Kvist +5 more
doaj +1 more source
Scientific Reports, 2022 Estrogen receptor alpha (ERα) signaling has beneficial skeletal effects in males. ERα signaling also affects other tissues, and to find bone-specific treatments, more knowledge regarding tissue-specific ERα signaling is needed.
Karin Horkeby +9 more
doaj +1 more source