Results 41 to 50 of about 219,075 (257)

The role of the P2X7 receptor on bone loss in a mouse model of inflammation-mediated osteoporosis

Bone Reports, 2017
In inflammatory autoimmune diseases, bone loss is frequent. In most cases, secondary osteoporosis is caused by treatment with systemic glucocorticoid. However, the pathogenesis behind the bone loss is presumed multifactorial.
T.M. Kvist, S. Syberg, S. Petersen, M. Ding, N.R. Jørgensen, P. Schwarz   +5 more
doaj   +1 more source

Phosphorylation of S122 in ERα is important for the skeletal response to estrogen treatment in male mice

Scientific Reports, 2022
Estrogen receptor alpha (ERα) signaling has beneficial skeletal effects in males. ERα signaling also affects other tissues, and to find bone-specific treatments, more knowledge regarding tissue-specific ERα signaling is needed.
Karin Horkeby, Helen H. Farman, Sofia Movérare-Skrtic, Vikte Lionikaite, Jianyao Wu, Petra Henning, Sara Windahl, Klara Sjögren, Claes Ohlsson, Marie K. Lagerquist   +9 more
doaj   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Vertebral HU value and the pectoral muscle index based on chest CT can be used to opportunistically screen for osteoporosis

Journal of Orthopaedic Surgery and Research
Background Existing studies have shown that computed tomography (CT) attenuation and skeletal muscle tissue are strongly associated with osteoporosis; however, few studies have examined whether vertebral HU values and the pectoral muscle index (PMI ...
Xiong-Yi Wang, Sheng Pan, Wei-Feng Liu, Yi-Ke Wang, Si-Min Yun, You-Jia Xu   +5 more
doaj   +1 more source

Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai, Jessica Fitzpatrick, Jing Li, Eric Roberts, Patricia Katz, Laura Plantinga, Gabriela Schmajuk, Jinoos Yazdany   +7 more
wiley   +1 more source

Leonid Borisovich Reznik. Obituary

Остеопороз и остеопатии, 2019
The Russian Osteoporosis Association, the editors of the journal Osteoporosis and Osteopathies, regretfully report that on May 26, 2019, a famous Russian doctor, professor, doctor of medical sciences, chief freelance traumatologist of the Omsk region ...
Editorial Board Osteoporosis and Bone Diseases
doaj  

The Effects of Denosumab Treatment on Pain and Function Beyond Bone Density in Patients With Postmenopausal Osteoporosis: A Prospective Study

Orthopaedic Surgery
Objective Postmenopausal osteoporosis (PMOP) leads to bone loss, fragility, and fractures, causing pain and reduced function. Effective treatment should improve bone mineral density (BMD), prevent fractures, and enhance quality of life.
Miao Zheng, Xiong‐Yi Wang, Ke‐Yu Zhu, Si‐Min Yun, Yi‐Ke Wang, Cheng‐Wei Weng, Dong‐Zhang, Qi Wei, You‐Jia Xu   +8 more
doaj   +1 more source

Romosozumab for the treatment of osteoporosis

Osteoporosis and Sarcopenia, 2018
Romosozumab, a specific inhibitor of sclerostin, is a unique approach to therapy for postmenopausal osteoporosis and related disorders. The elucidation of sclerostin deficiency as the molecular defect of syndromes of high bone mass with normal quality ...
Michael R. McClung
doaj   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Pulsed electromagnetic field prevents lumbar bone loss in orchiectomy mice without altering systemic iron metabolism

Frontiers in Bioengineering and Biotechnology
BackgroundThe therapeutic efficacies of pulsed electromagnetic fields (PEMFs) for postmenopausal osteoporosis are well established; however, their effects on male osteoporosis remain uncertain.
Jiancheng Yang, Yan Feng, Mingming Pan, Yuhong Zeng   +3 more
doaj   +1 more source