Results 71 to 80 of about 291,165 (296)

Pregnancy Associated Osteoporosis Leading to Vertebral Compression Fracture [PDF]

, 2016
To describe a patient with low back pain developed in the postpartum period and diagnosed as having vertebral compression fracture due to pregnancy and lactation associated osteoporosis.
Alper Sönmez, Berke Aras, Serdar Kesikburun, Emre Adıgüzel, Arif Kenan Tan, Birol Balaban   +5 more
core   +1 more source

Combination of 3D and 2D Small and Wide Angle X‐Ray Scattering Imaging Reveals Diminished Bone Quality in the Superior Human Femoral Neck Cortex

Advanced Materials, EarlyView.
Combined 2D and 3D X‐ray scattering imaging is used to analyse nanostructural properties in the inferior and superior cortex of 78 human femoral necks from 44 donors. The methodology allows for increased interpretation of nanostructure in a statistically relevant dataset, revealing nanostructural differences in anatomical locations critical to clinical
Torne Tänzer, Tatiana Kochetkova, Arthur Baroni, Mathieu Simon, Mads Carlsen, Santiago Fernandez Bordin, Manuel Guizar‐Sicairos, Philippe Zysset, Marianne Liebi   +8 more
wiley   +1 more source

Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database

Journal of Osteoporosis, 2011
Introduction. Regional differences for fracture risk of US Hispanics may vary by national origin. In California, where a majority of the Hispanic population is of Mexican descent, it is of interest to compare the FRAX absolute risk using the US Hispanic ...
Keaton M. Nasser, Augusto Focil, Stuart L. Silverman   +2 more
doaj   +1 more source

Dysmobility syndrome: a paradigm shift in fracture prevention

Bolʹ, Sustavy, Pozvonočnik, 2017
Fragility fractures engender major healthcare cost, reduce independence/quality and life and increase mortality risk. Despite availability of multiple therapies to reduce risk for future fracture, few patients are treated even following hip fracture ...
Neil Binkley, Diane Krueger
doaj   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

Advanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi, Felix Geng, Jan‐Noël Frenzke, Gregor Fuhrmann   +3 more
wiley   +1 more source

Pyrroloquinoline quinone targets senescent osteoclasts and reduces spinal pain and endplate degeneration in a lumbar spine instability mouse model

Journal of Translational Medicine
Background Pyrroloquinoline Quinone (PQQ) is a redox cofactor with potent antioxidant and anti-inflammatory properties. This study investigated the therapeutic potential of PQQ in alleviating spinal pain and degeneration in a lumbar spine instability ...
Qinghe Geng, Yan Geng, Ke Heng, Juan Zhai, Xingchen Song, Liangwei Sha, Yinuo Geng, Peiru Nie, Fanshuo Liu, Huaiyuan Zhai, Junli Huang, Yanhong Liu, Mei Li, Guoqiang Wang, Rui Geng, Kui Xue, Qilong Wang, Wanying Huang, Shuangshuang Suo, Huanyu Zhang, Ying Geng, Yuanji Yang, Junyun Lan, Hengsheng Hu, Shengnan Liu, Xiangfei Meng, Yilong Guo, Jie Li   +27 more
doaj   +1 more source

Mechanisms and management strategies for exacerbated bone loss following denosumab discontinuation

Frontiers in Aging
Denosumab is a first-line therapy for osteoporosis, yet the rebound increase in bone turnover markers, rapid bone loss, and elevated fracture risk following its discontinuation have become major challenges in clinical management.
Jiancheng Yang, Ming Yang, Yuhong Zeng
doaj   +1 more source

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

Advanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu, Bingwei Wang, Zhijie Su, Xiaoxv Han, Miao He, Yun Zhao, Yujia Hou, Daotong Li, Weiguang Zhang, Lihua Qin, Ke Wang, Yanchun Li, Yi Yan, Siwang Yu, Xiaoshuai Huang, Tairan Yuwen, Jianyuan Luo, Ruimao Zheng   +17 more
wiley   +1 more source

Opportunistic Assessment of Hip Fracture Risk Based on Chest CT

Orthopaedic Surgery
Objective Hip fracture (HF) has been described as the “last fracture of life” in the elderly, so the assessment of HF risk is extremely important. Currently, few studies have examined the relationship between imaging data from chest computed tomography ...
Xiong Yi Wang, Si Min Yun, Wei Feng Liu, Yi Ke Wang, Sheng Pan, You Jia Xu   +5 more
doaj   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source