Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal +3 more
wiley +1 more source
Deciphering stromal cell interactions in osteosarcoma highlights CDKN2A and MMP14 as novel diagnostic and therapeutic biomarkers. [PDF]
Peng X, Jiang H, Sun Y, Ge J, Luo Z.
europepmc +1 more source
Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima +6 more
wiley +1 more source
Delayed Aggressive Local Recurrence of Chondroblastic Osteosarcoma 3 Years After an Excellent Pathological Response: A Case Report. [PDF]
Hannan A +11 more
europepmc +1 more source
ABSTRACT Radiation therapy (RT) has emerged as a promising non‐surgical approach for treating canine adrenal tumours. This multi‐institutional, retrospective study describes clinical outcomes for 21 dogs having been prescribed a course of hypofractionated image‐guided intensity‐modulated RT (IMRT) entailing delivery of 25–35 Gy total in 5 fractions ...
Yen‐Hao Erik Lai +4 more
wiley +1 more source
A Phase 2 Trial of RANKL Antibody, Denosumab, in Two Cohorts of Patients with Recurrent/Refractory Osteosarcoma, a Report from the Children's Oncology Group. [PDF]
Janeway KA +16 more
europepmc +1 more source
ABSTRACT Elective neck dissection (END) and sentinel lymph node biopsy (SLNB) are suggested for nodal staging of canine head and neck malignancies (HNM). This study aims to compare the morbidity of END to SLNB. Seventy‐six client‐owned dogs with HNM that underwent END (n = 28) or SLNB (n = 48) in two institutions were retrospectively enrolled ...
Lavinia Elena Chiti +7 more
wiley +1 more source
Cholesterol and steroid synthesis pathways may be involved in the inhibition of osteosarcoma cell viability by calcium-sensing receptor antagonism. [PDF]
Wang L +7 more
europepmc +1 more source
Short-interval total femur replacement for infected distal femoral reconstruction. [PDF]
Chernov D +6 more
europepmc +1 more source
Early-onset metastatic fibroblastic osteosarcoma of the metatarsus in a young cat: a case report. [PDF]
Kiakojoori M +4 more
europepmc +1 more source

