This study presents a multifunctional Baghdadite ceramic implant integrating doxorubicin‐loaded liposomes via ion‐assisted plasma polymer coating for localized osteosarcoma therapy. The platform enables drug retention, sustained release, tumor cell inhibition, osteoconductivity, and antibacterial activity, offering a mechanically robust strategy for ...
Sally Kortam +8 more
wiley +1 more source
Statement of Retraction: MicroRNA miR-331-3p suppresses osteosarcoma progression via the Bcl-2/Bax and Wnt/β-Catenin signaling pathways and the epithelial-mesenchymal transition by targeting N-acetylglucosaminyltransferase I (MGAT1). [PDF]
europepmc +1 more source
[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway. [PDF]
Shu X +9 more
europepmc +1 more source
ABSTRACT Medical advances have increased cancer survival rates and the possibility of finding a cure. Hence, it is crucial to evaluate the impact of treatments both in terms of cure and prolongation of survival. To achieve this, we may use a Cox proportional hazards cure model.
Marta Cipriani +4 more
wiley +1 more source
Macrophage plasticity in the osteosarcoma tumor microenvironment: opportunities and challenges for immunotherapy. [PDF]
Li H, Liu C, Zhang B, Zhang Y, Liu Y.
europepmc +1 more source
Malignant Ovarian Germ Cell Tumor—Survival and Reproductive Outcomes and Patterns of Relapse
BLURB FOR ETOC: Patients presenting with advanced MOGCT can be offered fertility‐sparing surgery after neoadjuvant chemotherapy with no detriment in oncological outcome. ABSTRACT Background Malignant ovarian germ cell tumors [MOGCT] are rare cancers affecting young women and often present in advanced stages.
Sayak Dey +24 more
wiley +1 more source
Age-related real-world treatment patterns and outcomes of localised, high-grade osteosarcoma. [PDF]
Fujiwara T +5 more
europepmc +1 more source
Lactylation-driven metabolic reprogramming promotes osteosarcoma malignancy via HDGF-mediated proliferation and immune modulation. [PDF]
Hu S, Wu L, Wang J, Dai F.
europepmc +1 more source
ABSTRACT Methotrexate (MTX) is a folate antagonist widely used as a disease‐modifying antirheumatic drug (DMARD) in rheumatoid arthritis (RA), as well as in several malignancies and autoimmune disorders. Although low‐dose MTX (5–20 mg/week) is generally considered safe, it has a narrow therapeutic index, and toxicity can occur even at therapeutic doses,
Fatemeh Afra +7 more
wiley +1 more source
Effect of Osteoblast-Derived Extracellular Vesicles on Osteosarcoma Cells' Transcriptional Profile: Role of Shuttled miRNAs. [PDF]
Giacchi L +7 more
europepmc +1 more source

