Results 211 to 220 of about 126,514 (307)

CRISPR‐Cas9 Genome‐Wide Screening in Paediatric Cancer: Functional Genomics for Target Discovery and the Improvement of Existing Therapies

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 989-1004, July 2026.
ABSTRACT CRISPR‐Cas9 genome‐wide screening has been instrumental towards identifying novel targets for drug discovery in cancer research. However, much of this research has centred specifically on adult cancers, with paediatric cancers being underserviced by current research and screening.
Steven He   +2 more
wiley   +1 more source

Sclerotherapy for Aneurysmal Bone Cyst in Canine

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Percutaneous polidocanol sclerotherapy effectively treated an ABC in a 10‐year‐old German Shepherd's distal radius. This minimally invasive procedure resulted in radiographic healing by 8 weeks and complete resolution of lameness within 7 months. The findings suggest sclerotherapy is a promising alternative to invasive surgical management for canine ...
Pradip Chaudhari   +5 more
wiley   +1 more source

Ossifying spindled and epithelioid tumour: Expanding the clinical and morphologic spectrum of a recently described entity

open access: yesHistopathology, Volume 89, Issue 1, Page 163-173, July 2026.
Ossifying spindled and epithelioid tumour (OSET) can show unusual morphologic features, including minimal or absent peripheral ossification, eosinophil‐rich stroma, increased mitotic activity (≥5 mitotic figures per 10 high‐power fields), and necrosis.
Rayan M Sibira   +9 more
wiley   +1 more source

Magnetic Resonance Imaging Features of Intravascular Osteosarcoma Affecting the Ventral Internal Vertebral Venous Plexus Causing Cervical Myelopathy in a Dog

open access: yesVeterinary Radiology &Ultrasound, Volume 67, Issue 4, July 2026.
ABSTRACT A 10.5‐year‐old male castrated Standard Poodle was referred for the evaluation of chronic C6–T2 myelopathy. MRI revealed a severe asymmetric enlargement of the ventral internal vertebral venous plexus, intervertebral/vertebral veins, and possibly the C6 basivertebral vein, with secondary mild spinal cord compression.
Robert Wise   +3 more
wiley   +1 more source

Extraskeletal osteosarcoma in the rectus abdominis muscle: a case report. [PDF]

open access: yesJ Surg Case Rep
Nakayama K   +5 more
europepmc   +1 more source

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