Results 221 to 230 of about 171,941 (345)

Do alternative classification systems improve prognostication in phyllodes tumours of the breast? A comparative clinicopathological study

open access: yesHistopathology, EarlyView.
In this cohort, high stromal mitotic activity and malignant heterologous elements best predicted recurrence in breast phyllodes tumours. The WHO 5th Edition showed the strongest correlation with outcomes. Tan et al. showed near‐complete concordance, while the Refined Criteria overclassified malignancy without a clear prognostic refinement.
Yuri Merlotti Gomes   +13 more
wiley   +1 more source

SLC7A3 Expression Is Associated With Migration, Invasion, and Survival in Oral Squamous Cell Carcinoma

open access: yesJournal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral squamous cell carcinoma (OSCC) is an aggressive malignancy with limited prognostic biomarkers, in which metabolic reprogramming contributes to tumor progression. Amino acid transporters of the solute carrier family have emerged as key regulators of cancer biology; however, the role of solute carrier family 7 member 3 (SLC7A3 ...
Lilianny Querino Rocha de Oliveira   +7 more
wiley   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

open access: yesJournal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag   +6 more
wiley   +1 more source

Survival outcomes in dogs treated with vinorelbine‐based adjuvant treatment following surgical resection of grade II and III pulmonary carcinoma

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives Pulmonary carcinoma in dogs is commonly managed with surgical resection; however, the role of adjuvant chemotherapy for grade II and III carcinomas remains unclear. This retrospective multicentre study investigated the outcomes in dogs treated with vinorelbine‐based adjuvant treatment (as monotherapy or combined chemotherapy) following ...
N. Wong, L. Brockley, S. Rajan, J. Yu
wiley   +1 more source

Design, synthesis, and biological evaluation of diosgenin derivatives containing arylsulfonamide moieties as anti-osteosarcoma agents through modulation of the Hippo pathway [PDF]

open access: green
Xiao-Jie Si   +8 more
openalex   +1 more source

N‐methyl‐D‐aspartate receptor antagonists for controlling pain in dogs

open access: yesJournal of Small Animal Practice, EarlyView.
This is a mini review published by the World Small Animal Veterinary Association's Pain Committee. This article provides an assessment of the scientific evidence of N‐methyl‐d‐aspartate receptor antagonists for controlling pain in dogs while identifying current knowledge gaps.
P. W. Kronen   +6 more
wiley   +1 more source

Pharmacokinetics of Buccally Administered Cannabidiol and Oral Carprofen During Single‐ and Repeated‐Dose Administration in Dogs

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Cannabidiol (CBD) is increasingly used as an adjunct treatment for chronic pain in dogs, but information on repeated‐dose pharmacokinetics and potential interactions with commonly used analgesics remains limited. This study evaluated the pharmacokinetics of buccally administered CBD, its major metabolites, and orally administered carprofen in ...
Tilen Vake   +9 more
wiley   +1 more source

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