Results 11 to 20 of about 2,859 (123)

OTEH-1. Alternative RNA splicing modulates composition of ribosomes and determines spatial phenotype of glioblastoma cells [PDF]

Neurooncol Adv, 2021
Abstract Glioblastoma (GBM) is an extremely heterogeneous tumor and its different regions are populated with phenotypically distinct types of cancer cells. However, it is still unclear how multiple GBM populations arise from the originally homogenous group of tumor precursor cells.
Pavlyukov M, Larionova T, Bastola S, Shender V, Nakano I, Shakhparonov M.   +5 more
europepmc   +3 more sources

OTEH-11. Single Cell RNA Sequencing to identify cellular heterogeneity with in Pituitary Adenomas [PDF]

Neurooncol Adv, 2021
Abstract Pituitary adenomas (PA) are one of the most common primary brain tumors and comprise approximately 15% of brain neoplasms. Most PA are histologically benign, but can cause significant morbidity. Previous studies utilized whole genome and exome sequencing to identify a few somatic variants, but no recurrent mutations were ...
Jain S, Babikir H, Shamardani k, Diaz A, Aghi M.   +4 more
europepmc   +3 more sources

OTEH-5. Characterization of long-non coding RNA associated ceRNA network hub gene involved in glioblastoma multiforme lipid metabolism [PDF]

Neurooncol Adv, 2021
Abstract Background Glioblastoma multiforme (GBM) are the major death contributor in primary brain tumour. Despite having an improved diagnostic criterion by integrating both histological and molecular features such as Isocitrate Dehydrogenase (IDH) detection, the prognosis of GBM patients still ...
Rizalhanafi F, Ramli N, Narayanan V, Rashid K, Singh J, Ibrahim K.   +5 more
europepmc   +3 more sources

OTEH-3. Targeted Gene-Expression analysis during malignant transformation in primary and secondary malignant meningioma [PDF]

Neurooncol Adv, 2021
Abstract Background Malignant meningiomas comprise 2–5% of all meningiomas. The process of malignant transformation when benign meningiomas (WHO grade I-II) become malignant (WHO grade III) has not previously been investigated in sequential tumour surgeries.
Maier A, Meddis A, Haslund-Vinding J, Mirian C, Areskeviciute A, Nguyen P, Westergaard C, Melchior L, Munch T, Skjøth-Rasmussen J, Poulsgaard L, Ziebell M, Bartek J, Broholm H, Poulsen F, Gerds T, Scheie D, Mathiesen T.   +17 more
europepmc   +4 more sources

OTEH-9. scRNA sequencing of proneural GBM avatar model reveals acquisition of oncogenic transcriptional programming and infers a developmental path towards a genomically unstable state [PDF]

Neurooncol Adv, 2021
Abstract Glioblastomas (GBMs) are the most common malignant primary brain tumors, and the paucity of novel treatments warrants an investigation of its origins and development into aggressive, lethal tumors. Koga & Chaim et al. have recently shown that human pluripotent stem cells (hiPSCs) with different combinations of driver ...
Taylor B, Chaim I, Koga T, Miki S, Yee B, Yeo G, Furnari F.   +6 more
europepmc   +3 more sources

OTEH-2. High-dimensional analysis of spatial immune cell heterogeneity in glioblastoma reveals differences between contrast-enhancing and non-contrast-enhancing tumor rims [PDF]

Neurooncol Adv, 2021
Abstract Background Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. GBM remains an incurable disease, with a median survival ~20 months. Complex intercellular interactions within the tumor microenvironment and spatial heterogeneity have challenged and impeded therapeutic
Watson D, Bayik D, Grabowski M, Ahluwalia M, Mohammadi A, Lathia J.   +5 more
europepmc   +3 more sources

Perception Regarding the NICE Guideline on Antibiotic Prophylaxis against Infective Endocarditis Following Dental Procedures: A Cross-Sectional Study [PDF]

Antibiotics, 2023
This study explores the opinions of Malaysian clinical specialists on the antibiotic prophylaxis against infective endocarditis (IE) as described in the 2008 National Institute for Health and Care Excellence (NICE) guideline.
Siti Salmiah Mohd Yunus, Syed Nabil, Muhd Fazlynizam Rashdi, Abd Jabar Nazimi, Rifqah Nordin, Huann Lan Tan, Oteh Maskon, Hamat H. Che Hassan, Tzar Mohd Nizam Khaithir, Aznida Firzah Abdul Aziz, Yee Guan Ng, Ridwan Yeop Ismail, Roszalina Ramli   +12 more
doaj   +2 more sources

Directional Modulation of the Integrated Stress Response in Neurodegeneration: A Systematic Review of eIF2B Activators, PERK-Pathway Agents, and ISR Prolongers [PDF]

Biomedicines
Background and Objectives: The integrated stress response (ISR) is a convergent node in neurodegeneration. We systematically mapped open-access mammalian in vivo evidence for synthetic ISR modulators, comparing efficacy signals, biomarker engagement, and
Isabella Ionela Stoian, Daciana Nistor, Mihaela Codrina Levai, Daian Ionel Popa, Roxana Popescu   +4 more
doaj   +2 more sources

5th International Conference OTEH 2012 - defense technology (Proceedings review)

Vojnotehnički Glasnik, 2013
This article gives an overview of all papers and events at the Fifth International ScientificConference on Defense Technologies OTEH 2012 held in Belgrade, in the Military Technical Institute (VTI), from 18th to 19th September 2012.The paper review ...
Vlado Petar Đurković
doaj   +2 more sources

Effects of Swedish massage therapy on blood pressure, heart rate, and inflammatory markers in hypertensive women. [PDF]

Evid Based Complement Alternat Med, 2013
Swedish Massage Therapy (SMT) is known for its therapeutic relaxation effects. Hypertension is associated with stress and elevated endothelial inflammatory markers. This randomized control trial measured the effects of whole body SMT (massage group) or resting (control group) an hour weekly for four weeks on hypertensive women.
Supa'at I, Zakaria Z, Maskon O, Aminuddin A, Nordin NA.   +4 more
europepmc   +2 more sources