Results 91 to 100 of about 7,737,788 (301)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
American Studies as a Contemporary Disciplinary Practice
[sic], 2014 The departure point of this article is that however one conceives the practice of American Studies one has to recognize that it is a disciplinary practice.
Stipe Grgas
doaj +1 more source
PLoS ONE, 2020 The autism spectrum disorder (ASD) is a complex disorder encompassing a broad phenotypic and genotypic variability. The short (S)/long (L) 5-HTTLPR polymorphism has a functional role in the regulation of extracellular serotonin levels and both alleles ...
D L Nuñez-Rios +4 more
doaj +1 more source
Influence and Presence, Depth and Surface: Studying the American Impact on Other Countries
American Studies in Scandinavia, 2003 Influence and Presence, Depth and Surface : Studying the American Impact on Other ...
openaire +1 more source
Masculinity Studies on Two Continents and in Two Eras: Thomas A. Hickey in Victorian Dublin and Progressive Era America, 1868-1925 [PDF]
, 2014 This project added to a much larger work, a definitive biography of Thomas Aloysius Hickey (1868-1925) in the genre of the “New Biography,” which means by necessity using more than collections of letters, diaries, and writings--work that is attentive to ...
Stanton, Alanna M.
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Depression among Asian-American Adults in the Community: Systematic Review and Meta-Analysis.
PLoS ONE, 2015 ObjectivesIn this systematic review, we provide an overview of the literature on depression among Asian-Americans and explore the possible variations in depression prevalence estimates by methodological and demographic factors.MethodsSix databases were ...
Hee Jun Kim +4 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Acervo, 2018 Regina A. Root (raroot@wm.edu) is Professor of Hispanic Studies at William & Mary, the historic university in Williamsburg, Virginia. She is an international expert known for her work on fashion, textiles, and Latin American cultural production.
Maria do Carmo Rainho +1 more
doaj
Journal of Medical Internet ResearchBackgroundAlthough tobacco use has significantly declined in the general population, traditional tobacco use treatment uptake and success rates remain disproportionately low among people who identify as African American/Black ...
Emily Hichborn +11 more
doaj +1 more source