Results 51 to 60 of about 31,140,139 (245)
Practicality of algorithmic number theory [PDF]
, 2013 textThis report discusses some of the uses of algorithms within number theory. Topics examined include the applications of algorithms in the study of cryptology, the Euclidean Algorithm, prime generating functions, and the connections between algorithmic
Taylor, Ariel Jolishia
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
ADVANCE OF SMARANDACHE APPROACH TO SOLVING SYSTEMS OF DIOPHANTlNE EQUATIONS [PDF]
, 2003 By developing F. Smarandache (algebraic) approach to solving systems of Diophantine equations we elaborate a set of new computative algorithms and analytical formulae, which may be used for fmding numerical solutions of some combinatorial and number ...
CHEBRAKOV, Y.V.
core +1 more source
Notes on nilspaces: algebraic aspects
Discrete Analysis, 2017 Notes on nilspaces: algebraic aspects, Discrete Analysis 2017:15, 59 pp. One of the fundamental insights in modern additive combinatorics is that there is a hierarchy of notions of "pseudorandomness" or "higher order Fourier uniformity" that can be ...
Pablo Candela
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The ABC's of Number Theory [PDF]
, 2007 The ABC conjecture is a central open problem in modern number theory, connecting results, techniques and questions ranging from elementary number theory and algebra to the arithmetic of elliptic curves to algebraic geometry and even to entire functions ...
Elkies, Noam
core
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Combinatorial grid sequencing: An axiomatic framework for grid-based combinatorial dynamics
This work introduces Combinatorial Grid Sequencing (CGS), an axiomatic combinatorial theory inspired by certain patterns of concrete-casting works in multi-storey building construction.
Christoporus A. A. Ohmar +2 more
core +1 more source