Results 61 to 70 of about 31,140,139 (245)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
2017 and 2018 Combinatorial and Additive Number Theory (CANT) workshops
, 2020 Based on talks from the 2017 and 2018 Combinatorial and Additive Number Theory (CANT) workshops at the City University of New York, these proceedings offer 17 peer-reviewed and edited papers on current topics in number theory. Held every year since 2003,
Nathanson, Melvyn
core +1 more source
, 2000 In this thesis, we study neighbourhoods of exponential size that can be searched in polynomial time. Such neighbourhoods are used in local search algorithms for classes of combinatorial optimisation problems.
Congram, Richard K.
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Lower bounds for incidences with hypersurfaces
Discrete Analysis, 2016 Lower bounds for incidences with hypersurfaces, Discrete Analysis 2016:16, 14pp. A fundamental result in combinatorial geometry, the Szemerédi-Trotter theorem, states that among any $n$ points and $m$ lines in $\mathbb R^2$ there can be at most $O((mn)^{
Adam Sheffer
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Formation of a heterogeneous group of UAVS with a reasonable number of false and real drones
Радіоелектронні і комп'ютерні системиThe subject of scientific research is the joint use of false and real unmanned aerial vehicles (UAVs) as part of a heterogeneous group of UAVs to perform military tasks. This article aimsto determine the appropriate number of false and real drones (UAVs)
Volodymyr Prymirenko +5 more
doaj +1 more source
Fuglede's conjecture on cyclic groups of order $p^nq$
Discrete Analysis, 2017 Fuglede's conjecture on cyclic groups of order $p^nq$, Discrete Analysis 2017:12, 16 pp. A conjecture of Fuglede from 1974 states that a measurable set $E\subset \mathbb R^n$ of positive Lebesgue measure tiles $\mathbb R^n$ by translations if and only ...
Romanos Diogenes Malikiosis +1 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Dynamic Combinatorial Libraries: From Exploring Molecular Recognition to Systems Chemistry [PDF]
, 2013 Dynamic combinatorial chemistry (DCC) is a subset of combinatorial chemistry where the library members interconvert continuously by exchanging building blocks with each other.
Otto, Sijbren, +9 more
core +1 more source