Results 151 to 160 of about 3,998,003 (341)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Rebordering the borders created by multidisciplinary sciences: A study [PDF]
Emergence of “Glass ceiling” like phenomena in the minds of professionals doing research in a multidisciplinary subject needs to be studied. For an example, computational neurosciences(CNS) comprises of neurology, cognitive science, psychology, computer ...
Kannan, Srinivasan
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Journal of Multidisciplinary HealthcareMingzhao Wang,1 Ran Liu,1 Joseph Luttrell IV,2 Chaoyang Zhang,2 Juanying Xie1 1School of Computer Science, Shaanxi Normal University, Xian, People’s Republic of China; 2School of Computing Sciences and Computer Engineering, University of Southern ...
Wang M +4 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Ostium, 2013 Nagy, Á.: The Characteristics of Terminology of Sciences in relation to Family from point of view of Terminological Extraction According to Eugen Wüster, terms are lexical units that belong to a scientific domain where they are connected to a concept ...
Ágoston Nagy
doaj
Proceedings of the 25th Australasian Computing Education Conference, 2023 Shamima Nasrin Runa +3 more
openaire +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Functions and Mathematical Modelling with Spreadsheets
Spreadsheets in Education, 2017 In this paper we intended to show how it is possible to encourage the use of computers in the learning of Mathematics, using development environments such as spreadsheets, with which teachers and students can develop interactive computer applications ...
Margarida Oliveira, Suzana Nápoles
doaj
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source