Results 161 to 170 of about 611,402 (306)

Determinants of digital health literacy among health professionals: Evidence from public and private hospitals in Eastern Ethiopia. [PDF]

PLoS One
Asfaw E, Shiferaw T, Tolera M, Weldesenbet AB, Seid M.   +4 more
europepmc   +1 more source

Toward Automated Validation of Computer Programs

, 2014
[[fileno]]2030201010077[[department ...
W. T. Chen
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The total eclipse of bioinformatics: From disruption to convention, and a gentle warning. [PDF]

PLoS Comput Biol
Ouzounis CA.
europepmc   +1 more source

Prospects and Challenges for the Computational Social Sciences

, 2017
Computational social sciences (CSS) refer to computer-enabled investigations of human behaviour and social interaction. They include three main components - (i) computational modelling and social simulation, (ii) the analysis of digital traces of online ...
Farjam, Mike, Bravo, Giangiacomo
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Computer-aided detection for radiological disease severity classification on chest radiograph in children with intra-thoracic tuberculosis. [PDF]

PLOS Glob Public Health
Palmer M, Derks I, Schaaf HS, Goussard P, Jaganath D, Kik SV, Gibb DM, Turkova A, Walters E, van der Zalm MM, Hesseling AC, Seddon JA.   +11 more
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

An empirical exploration of the diversified R ecosystem. [PDF]

PLoS One
Huang TY, Lou Z.
europepmc   +1 more source

FARM COMPUTER ADOPTION IN THE GREAT PLAINS

Computers change rapidly, yet the last survey on computer use in agriculture was in 1991. We surveyed Great Plains producers in 1995 and used logit analysis to characterize adopters and non-adopters.
Hoag, Dana L., Ascough, James C., Frasier, W. Marshall   +2 more
core