Results 161 to 170 of about 3,998,003 (341)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
CAD, BIM, GIS and other tricks of the computer science in the education of the Building Engineer
, 2011 Revisione internazionale- relazione a invito- chair sessione S8T The paper aims to develop some thoughts on the upgrade implemented in the disciplines of drawing from the latest forms of digital representation, commenting on the experiences under way in some university courses included in the learning curriculum provided to engineering students with ...
NOVELLO, Giuseppa +1 more
openaire +1 more source
, 2019 Revista Antioqueña de las Ciencias Computacionales y la Ingeniería de Software RACCIS, 8(2), 16-22.
openaire +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
NANOSCIENCES IN LIBERAL ARTS COLLEGES: CURRICULUM EMBEDDING AND PROGRAM’S INTEGRATION
Momento, 2018 This communication discusses an approach for teaching about nanosciences from the perspective of the School of Sciences at St. Thomas University with a “Liberal Art” type of education, where also there is not a major in Physics neither room within the ...
David Quesada
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Revista MENDIVE, 2008 The training process has been researched and discussed in multiple instances, as increasingly urgent need to prepare people for the task they perform. Technological progress now allows to consider other alternatives for the training of specific personnel.
Eniel Lorenzo Garcia +1 more
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source