Results 61 to 70 of about 21,635,005 (257)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Early Childhood Longitudinal Study - United States (ECLS-K) Instrument Matrix
, 2013 The Early Childhood Longitudinal Study [United States] (ECLS-K) uses many instruments to collect data. This document provides a complete list of the ECLS-K instruments indexed in the Research Connections' database.
Child Care & Early Education Research Connections
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The Role Played by Extra-mathematical Connections in the Modelling Process
Avances de Investigación en Educación MatemáticaLiterature review in Mathematics Education on connections makes evident the necessity of delving into extra-mathematical connections. In this line, we answer the question: What types of mathematical connections are required to develop the modelling ...
Carlos Ledezma +2 more
doaj +1 more source
Head Start Family and Child Experiences Survey (FACES) Instrument Matrix
, 2014 The Head Start Family and Child Experiences Survey (FACES) uses many instruments to collect data. This document provides a complete list of the FACES instruments indexed in the Research Connections' database.
Child Care & Early Education Research Connections
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Head Start Impact Study (HSIS) Instrument Matrix
, 2012 The Head Start Impact Study (HSIS) uses many instruments to collect data. This document provides a complete list of the HSIS instruments indexed in the Research Connections' database.
Child Care & Early Education Research Connections
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Connections PCF9 Edition – Day 2
, 2019 Relive the Day 2 highlights of the ninth Pan-Commonwealth Forum (PCF9) with this special edition of ...
Commonwealth of Learning
core +1 more source