Results 71 to 80 of about 21,635,005 (257)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Connections PCF9 Edition – Day 3
, 2019 Relive the Day 3 highlights of the ninth Pan-Commonwealth Forum (PCF9) with this special edition of ...
Commonwealth of Learning
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Connections (vol. 21, PCF8 edition 3) [PDF]
, 2016 A special edition of Connections, published at the Eighth Pan-Commonwealth Forum on Open Learning on 30 November ...
core +1 more source
Connections PCF9 Edition – Day 1
, 2019 Relive the Day 1 highlights of the ninth Pan-Commonwealth Forum (PCF9) with this special edition of ...
Commonwealth of Learning
core +1 more source
Functional maps of neocortical local circuitry
Frontiers in Neuroscience, 2007 This review aims to summarize data obtained with different techniques to provide a functional map of the local circuit connections made by neocortical neurones, a reference for those interested in cortical circuitry and the numerical information required
Alex M Thomson, Christophe Lamy
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Other title: Connections, 2024
Annual cumulation of 2024 issues4 Kansas Public Health Conference preview -- Reduce exposure to Bisphenol A (BPA) -- News & Resources -- Training & Conferences -- Job Postings -- 2024 Kansas Public Health breaks another attendance record -- New public ...
Bureau of Community Health Systems--Kansas. Department of Health and Environment
core +1 more source