Results 71 to 80 of about 2,823,513 (292)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The Role Played by Extra-mathematical Connections in the Modelling Process
Avances de Investigación en Educación MatemáticaLiterature review in Mathematics Education on connections makes evident the necessity of delving into extra-mathematical connections. In this line, we answer the question: What types of mathematical connections are required to develop the modelling ...
Carlos Ledezma +2 more
doaj +1 more source
Identification of structural interface characteristics using component mode synthesis [PDF]
The inability to adequately model connections has limited the ability to predict overall system dynamic response. Connections between structural components are often mechanically complex and difficult to accurately model analytically. Improved analytical
Huckelbridge, A. A., Lawrence, C.
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Sharing the Love, Feeding the Hungry [PDF]
, 2019 The biblical injunction to share one’s bread with the poor is for Christians intimately linked with the Eucharist and the Eucharist with the upbuilding of the Church. We will explore New Testament and other early Christian insights into these fundamental
Bradshaw, Paul F.
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
The Visual Callosal Connection: A Connection Like Any Other?
Neural Plasticity, 2013 Recent work about the role of visual callosal connections in ferrets and cats is reviewed, and morphological and functional homologies between the lateral intrinsic and callosal network in early visual areas are discussed. Both networks selectively link distributed neuronal groups with similar response properties, and the actions exerted by callosal ...
openaire +3 more sources
Term-based composition of security protocols
, 2008 In the context of security protocol parallel composition, where messages belonging to different protocols can intersect each other, we introduce a new paradigm: term-based composition (i.e.
Genge, Bela +3 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source