Results 131 to 140 of about 3,323,942 (317)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Accommodating multiculturalism and biculturalism in Aotearoa New Zealand: implication for language education. [PDF]

open access: yes, 2002
The field of language education in Aotearoa New Zealand, as elsewhere, has developed significantly since its early and almost exclusive focus on the acquisition of English literacy in schools.
May, Stephen
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Glocalization : Art education in Taiwan [PDF]

open access: yes, 2010
[[abstract]]Taiwan has always been subject to globalizing influences. In the past twenty years, the rapid development of information technology and increasing cross-cultural interactions has catalyzed a new ”global village” consciousness.
Wang, L.Y. ; Kuo, A.
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Other title: Part B annual performance report [PDF]

open access: yes, 2004
Annual; Began with Reporting period July 1, 2002/June 30, 2003.; Submitted to the U.S. Office of Special Education Programs (OSEP).; Volumes for reporting period July 1, 2002/June 30, 2003- also called ...
Connecticut. Bureau of Special Education.
core  

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

OTHER TITLE: 2004-2005 Accountability Report. [Kansas State Board of Education Annual Report, 2004-2005]. Kansas State Department of Education Annual Report [PDF]

open access: yes, 2005
"On the surface, the news concerning the academic performance of Kansas students appears good. Achievement is high, performance gaps are narrowing, and the state continues to do well against the rest of the nation on national measures.
Kansas. State Board of Education
core  

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