Results 111 to 120 of about 28,055,288 (354)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

After the education disciplines: teaching theory on-line.

open access: yes, 2003
Like all social theorising, the academic study of education is 'reflexive'- complicated by the fact of our immersion in it. This paper discusses an on-line version of an undergraduate teacher-education course, 'Social Issues in New Zealand Education ...
Middleton, Sue
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EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Other title: Business Practices of the Kansas State Department of Education

open access: yes, 2011
application/pdfA set of 6 documents provided by the Kansas State Department of Education with resources and information on various Business Practices.Kansas State Department of Education Technology Plan (December 05, 2011) -- Kansas State Department of ...
Kansas. State Department of Education.
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Hutterite education : teacher perceptions of student performance [PDF]

open access: yes, 1994
ix, 80 leaves : ill. ; 29 cm.The unique experience of being a public school teacher on a Hutterite colony has proven problematic for various reasons in the area of student eval uation. Hut teri te student achievement as undertaken by Alberta Education
University of Lethbridge. Faculty of Education   +1 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

A Quantitative Analysis of Seaplane Accidents from 1982-2021

open access: yesInternational Journal of Aviation, Aeronautics, and Aerospace
This study aimed to assess and analyze all historical National Transportation Safety Board accident reports since 1982. For analysis, reports were bisected into seaplane (float, amphibian, and hull) and non-seaplane groups.
David C. Ison
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Other title: Vocational Education Accountability Report

open access: yes, 1986
"The concept of accountability in vocational education has two primary concerns in the responsibility of vocational education: (1) to provide programs which will develop or improve individual vocational skills and (2) to efficiently utilize the various ...
Kansas. State Department of Education.
core  

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