Results 231 to 240 of about 3,323,942 (317)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Normative cognitive test performance and typical error patterns among American Indian older adults: The Strong Heart Study. [PDF]

Neuropsychology
Suchy-Dicey AM, Rhoads K, French B, Buchwald D, Longstreth WT.   +4 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The other as reference point of education in Europe

Revista Española de Pedagogía
Christoph Desconocido, Wulf. Desconocido
doaj   +1 more source

Education needs in oxygen therapy for individuals with interstitial lung disease. [PDF]

BMJ Open Respir Res
Rowland SD, Sharpe H, Ferrara G, Johannson KA, Kalluri M, Thompson S, Stickland MK.   +6 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Understanding the effect of educational attainment on the risk of retinal detachment: a Mendelian randomization mediation analysis. [PDF]

Int J Retina Vitreous
Katsimpris A, Baumeister SE, Baurecht H, Blaikie A, Goudie C, Tatham AJ, Nolde M.   +6 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

What is the interplay between self-care confidence, professional support and health literacy among UK adults? A cross-sectional online survey study. [PDF]

BMJ Open
Smith P, Altalib S, Al Ammouri M, El-Osta A.   +3 more
europepmc   +1 more source