Results 41 to 50 of about 6,615,277 (218)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Statutory guidance : funding arrangements for 16–19 education and training [PDF]

open access: yes, 2011
"This document has been prepared by the Young People’s Learning Agency as statutory guidance under the ASCL Act 2009 to describe how a simplified allocations and funding system for 16-19 education and training will operate for the 2012/13 academic year ...

core  

Making the Grade [PDF]

open access: yes, 2016
With its July 2015 announcement of the Second Chance Pell Pilot Program, the U.S. Department of Education ushered in what could be a new era of expanded opportunities for postsecondary education in our nation's prisons. The Second Chance Pell Pilot makes
Fred Patrick   +2 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Redistribution through Education and Other Transfer Mechanisms [PDF]

open access: yes
Educational subsidies are frequently justified as a method of altering the income distribution. It is thus natural to compare education to other tax-transfer schemes designed to achieve distributional objectives.
Charles Ka Yui Leung   +2 more
core  

Catalysts for Change: Three Case Studies of Quality Education Worldwide [PDF]

open access: yes, 2007
Public education is the cornerstone of democracy and is absolutely fundamental to a democratic, civil and prosperous society. Beyond the boundaries of the United States, other countries are working to provide quality education to their children through ...

core  

Gramsci and the politics of education [PDF]

open access: yes, 2014
This paper deals with aspects of Antonio Gramsci’s thinking on education and related cultural work, highlighting issues such as those of effective curricula, different forms of educators/intellectuals, work-oriented education and popular education which ...
Mayo, Peter
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Has education lost sight of children? [PDF]

open access: yes, 2018
The reflections presented in this chapter are informed by clinical and personal experiences of school education in the UK. There are many challenges for children and young people in the modern education system and for the professionals who support them ...
A Bandura   +72 more
core   +1 more source

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