Results 81 to 90 of about 28,055,288 (354)

Education-for-Myself and Education-for-the Other: The Right to Freedom of Education and Mikhail Bakhtin’s Experience

Dialogic Pedagogy, 2020
The article contains reflections on the problem which has arised in Eugene Matusov's article on freedom of education, and considers the experience of Mikhail Bakhtin as an example of the way the right to the freedom can be fulfilled.
Oleg Osovsky, Vera Kirzhaeva, Ekaterina Chernetsova, Elizaveta Maslova   +3 more
doaj   +1 more source

Perceptions and usage of AI chatbots among students in higher education across genders, academic levels and fields of study

Computers and Education: Artificial Intelligence
AI chatbots have ignited discussions and controversies about their impact on teaching and learning practices in higher education. This study explores students ’ adoption and perceptions of ChatGPT and other AI chatbots in higher education.
Christian Stöhr, Amy Wanyu Ou, Hans Malmström   +2 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Myocardial infarction in patients with HIV infection: incidence, risk factors, pathogenesis, clinical performance and treatment

Российский кардиологический журнал
HIV infection increases the risk of premature myocardial infarction (MI) and other atherosclerotic cardiovascular diseases, which are the main noncommunicable cause of death in HIV-infected patients.
K. V. Protasov, E. S. Eniseeva, Yu. K. Plotnikova   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A cross-sectional investigation of the relationships education, certification, and experience have with knowledge, skills, and abilities among aviation professionals

International Journal of Aviation, Aeronautics, and Aerospace, 2016
The aviation industry is a complex system with many different segments and as such, makes hiring the right person a complicated endeavor. Previous research suggested that knowledge, skills, and abilities (KSAs) are composed of elements that include ...
Daryl Watkins, Jason M Newcomer, Matthew P. Earnhardt, James W Marion, Rose A Opengart, Aaron M Glassman   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

A Usability Study for Electronic Flight Bag (EFB) Flight Planning Applications on Tablet Devices for Ab-initio Pilots

International Journal of Aviation, Aeronautics, and Aerospace, 2017
The proliferation of mobile technology has prompted the use of tablet devices in the cockpit and during ground operations in general aviation. Due to the increase in affordable and reliable hardware (i.e.
Jeff Schwartzentruber
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source