Results 101 to 110 of about 1,849,736 (267)
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
The mechanical engineering curriculum, at both the undergraduate and postgraduate levels, has been revised twice in the last decade. Despite these updates, its core foundation remains based on older models.
Jafar Ghazanfarian
doaj +1 more source
STANDARDS OF BELARUS IN THE FIELD OF PHOTOMETRY
The article introduces a standard base of Belarus in the field of photometry. Scientific research conducted on the standards can be interest for professionals working in the areas of mechanical engineering, instrument, medicine, agriculture and other.
N. V. Bakovets +3 more
doaj +1 more source
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Advances of natural fiber composites in diverse engineering applications—A review
This paper emphasizes the significant usage of natural fiber as a reinforced composite in the potential engineering field. Mechanical, civil, textile, agricultural, and other engineering sectors have already initiated the utilization of natural fiber in ...
Fardin Khan +6 more
doaj +1 more source
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
New trends in Reverse-Engineering: Augmented-Semantic models for redesign of existing objects [PDF]
sous la coordination de Paolo BartoloInternational audienceReverse engineering is an approach that is used in many domains like electrical engineering, computer sciences and many others.
Bernard, Alain +3 more
core +1 more source
Molecular motors: design, mechanism and control
Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which synthesize ...
Chowdhury, Debashish
core +1 more source

