Results 71 to 80 of about 1,856,164 (287)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Design of a wrist and operator interface for an agricultural manipulator : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Engineering and Automation at Massey University [PDF]

open access: yes, 2000
Roadside mowing and tree pruning has always been a job that most people would consider as unpleasant. This project is concerned with the development of a system to make these tasks simpler, safer and more pleasant for the operator.
Noaro, Adrian Peter Charles
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Mechanical Engineering: Medium-Sized Companies with Highest Savings Potential [PDF]

open access: yes
The German mechanical engineering industry, dominated by medium-sized companies, is greatly successful - both on the domestic and on the international market.
Alexander S. Kritikos   +1 more
core  

Raising sector skills levels : how responsive is local training supply? [PDF]

open access: yes, 2005
This UK study examines the extent and nature of any mismatches between the training requirements of employers and the local provision of vocational education and training (VET).
Mason, Geoff   +2 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Mechanics+Mechanical Engineering: Algorithm of Intensive Innovational Development

open access: yesМеханика машин, механизмов и материалов, 2007
The base directions of realization of the State program of country innovational development for 2006—2010 years in the field of mechanical engineering, which are coordinated and carried out within the framework of the State complex goal-oriented ...
V.I. Semashko, M.S. Vysotsky
doaj  

A CASE STUDY IN PROJECT BASED LEARNING USING FLOW VISUALISATION [PDF]

open access: yesJournal of Engineering Science and Technology, 2007
Engineering Design modules, usually introduced in the first and second year’s undergraduate Mechanical Engineering courses, present a unique platform to practice the Project Based Learning (PBL).
MUSHTAK AL-ATABI, S.B. CHIN
doaj  

Recent research and development of structural control in Japan

open access: yesJapan Architectural Review, 2019
In Japan, structural control is widely recognized as a fundamental technology for exceeding the performance limitations of conventional earthquake/wind‐resistant buildings.
Yoshiki Ikeda   +3 more
doaj   +1 more source

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