Results 111 to 120 of about 3,865,257 (306)

The dialogue with farmers [PDF]

, 2011
This report covers the project outcome Deliverable 4.2 ‘Analysis completed after a joint effort to identify possibilities in each country as how to facilitate the best possible dialogue regarding animal health and welfare’ as part of the European CORE ...
Brinkmann, Jan, Gratzer, Elisabeth, Henriksen, Britt I. F., Ivemeyer, Silvia, Leeb, Christine, March, Solveig, Mejdell, Cecilie, Nicholas, Phillipa, Roderick, Stephen, Smolders, Gidi, Stöger, Elisabeth, Vaarst, Mette, Walkenhorst, Michael, Whistance, Lindsay, Winckler, Christoph   +14 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Therapeutic potential of polyphenols against aging- induced idiopathic pulmonary fibrosis (IPF) via Bioinformatics analysis

Phytomedicine Plus
Background: Hyperactivation of Akt/mTORC1 is known to be the mechanistic driver for idiopathic pulmonary fibrosis (IPF) induction in elderly population. Stimulation of Aryl hydrocarbon receptor (AhR) under physiological stress is largely associated with ...
Ankit Tripathi, Deepika Tripathi, Manish Shukla, Meenakshi Sharma   +3 more
doaj   +1 more source

Seaweed Aquaculture and Marine Biotechnology [PDF]

, 2016
Macroscopic marine algae, typically known as macroalgae or seaweeds, form an important living resource of the oceans, as primary producers. People have collected seaweeds for food, both for humans and animals for millennia.
Gonçalves Pereira, Rui
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Capparis cartilaginea Decne. as a natural source of antioxidant, anti-inflammatory, and anti-cancer herbal drug

Phytomedicine Plus
Background: Capparis cartilaginea Decne.(C. cartilaginea Decne.) a medicinally important plant that belongs to the family Capparaceae. Traditionally the fruit, leaf, and root have been believed to show anti-inflammatory effects and can also be used as ...
Faten Hameed Thamer, Alaa.M. Al-opari, Ahmed M.S. Al-Gani, Esmat A. Al-jaberi, Fahmi A. Allugam, Hadeel H. Almahboub, Hithm M. Mosik, Huda H. Khalil, Mamon M. Abduljalil, Mohammed Y. Alpogosh, Muneef A. Albathigi, Noah A. Noordeen   +11 more
doaj   +1 more source

Research trends in nanotechnology studies across geo-economic areas [PDF]

The purpose of this paper is to analyze the current temporal and spatial research trajectories in nanoscience and nanotechnology studies in order to display the worldwide patterns of research fields across main economic players.
Diego Margon, Mario Coccia, Ugo Finardi
core  

An Environmental Science and Engineering Framework for Combating Antimicrobial Resistance [PDF]

, 2018
On June 20, 2017, members of the environmental engineering and science (EES) community convened at the Association of Environmental Engineering and Science Professors (AEESP) Biennial Conference for a workshop on antimicrobial resistance.
Alcalde, Reinaldo E., Alvarez, Pedro J.J., Ashbolt, Nicholas, Bischel, Heather, Capiro, Natalie L., Crossette, Emily, Frigon, Dominic, Grimes, Kassandra, Haas, Charles N., Ikuma, Kaoru, Kappell, Anthony D., Kimbell, Lee K., LaPara, Timothy M., Li, Mengyan, Li, Xu, McNamara, Patrick J., Navab-Daneshmand, Tala, Pruden, Amy, Raskin, Lutgarde, Riquelme, Maria Virginia, Seo, Youngwoo, Sobsey, Mark D., Sozzi, Emanuele, Vikesland, Peter, Wigginton, Krista, Zhou, Zhi   +25 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Alkaloid-rich extract of Lannea egregia leaf protect against cardiomyopathy in streptozotocin-induced type 2 diabetic rats

Phytomedicine Plus
Background: Lannea egregia leaf has been used locally for the management of diseases with limited scientific support. Hence, the cardiomyopathy protective ability of an alkaloid-rich extract of L.
B.O. Ajiboye, I.M. Folorunso, K.I. Akinfemiwa, B.E. Oyinloye, O.E. Lawal, O.A. Ojo, M. Ezema, O.R. Ajuwon, E.A. Ardekani   +8 more
doaj   +1 more source