Results 91 to 100 of about 3,865,257 (306)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Systems medicine, an approach in a framework to guide development of preventative, diagnostic and treatment methods for Covid-19 and other complex or novel diseases

, 2020
The Covid-19 has plunged the world into a pandemic where there is no specific cure yet. Scientists around the world are researching and running trials to find highly effective prevention methods and cure. There are three major existing medical approaches which have developed systematic methods to diagnose ,prevent and treat diseases , the TCM, evidence
openaire   +1 more source

Asthma-Related Hospitalization and Emergency Room Visits in Oakland [PDF]

, 2017
The City of Oakland has seen diminished childhood asthma rates. During the last few years more children have been able to qualify for Medi-Cal and other health insurance plans under the Affordable Care Act (ACA).
Varela, Alondra
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Comparing non-fatal health across countries: Is the US medical system better?. [PDF]

The primary focus of the paper is to assess whether the US, which spends significantly more than any other country in health care, has better health outcomes.
Cutler, David M., Mas, Nuria
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Experimental Study on Antidotal Activity of Musa × paradisiaca Linn. in Cobra Poison on Wistar Strain Albino Rats

Journal of Ayurveda
Introduction:Snake bite is an acute emergency which requires proper care and treatment. Today, the management of snake bites is done by administering anti-snake venom (ASV). The scarcity of ASV contributes to fatality. This scarcity of ASV is a result of
V. Revathy, S. Ravikrishna, Sudhakar Bhat, K. Sreejith, Chaithra Hebbar   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Possible therapeutic effect of frankincense (Gum olibanum) and myrrh (Commiphora myrrha) resins extracts on DEN/CCL4 induced hepatocellular carcinoma in rats

Phytomedicine Plus
Background: Liver cancer is a prominent global health concern characterized by prevalent and unregulated exposure to ubiquitous environmental hazards.
Amira M. Elmoslemany, Mohamed Elzallat, Mai Hussein Abd-Elfatah, Dina Mostafa Mohammed, Eman E.Abd Elhady   +4 more
doaj   +1 more source

Traditional medicine in sub-Saharan Africa : its importance and potential policy options [PDF]

This report indicates that about 20 percent of Africans who seek medical care first consult traditional healers. Patients tend to consult modern health care services for infectious or acute diseases, or those for which modern health care has been shown ...
DeJong, Jocelyn
core