Results 101 to 110 of about 2,020,687 (315)

The impact of acupuncture on the brain function of patients with mild to moderate major depressive disorder: a randomized controlled trial protocol

BMC Complementary Medicine and Therapies
Introduction Major depressive disorder (MDD) is a common mental disease that significantly impact the daily lives of those affected. Acupuncture has shown promising therapeutic effects in the treatment of MDD, but its underlying mechanisms remain unclear.
Bin Yang, Runqing Miao, Tianyu Wang, Fengya Zhu, Wuyu Li, Yang Liu, Jie Wu   +6 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Effects of percussive massage therapy on fascia echo intensity and fascia thickness in firefighters with chronic non-specific low back pain: a randomized controlled trial

BMC Complementary Medicine and Therapies
Background Chronic non-specific low back pain (CNSLBP) is prevalent among firefighters and may negatively affect their job performance. Alterations in the thoracolumbar fascia (TLF) structure are associated with CNSLBP.
Chao Yang, Ying Li, Wiraphong Sucharit, Wichai Eungpinichpong, Xingyu Huang   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Photo-physical characterizations and evaluation of in-vitro antioxidant, anti-inflammatory and antidiabetic potentials of green synthesized ackee (Blighia sapida) selenium nano-particles

BMC Complementary Medicine and Therapies
Background Green synthesized nanoparticles have recently gained significant medicinal applications and oftentimes outperform their green sources. Selenium is of fundamental importance to human health, stemming from its distinctive physicochemical ...
Omodele Ibraheem, Olubukola Helen Oyeniran, Oluwatobiloba Moses Ogundipe, Eunice Oluwabukunmi Abe, Temitope Adenike Oyedepo, Kehinde Oluseun Sodeinde, Stephen Oluwaseyi Damola, Tosin Benjamin Adeola   +7 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Effect and mechanisms of shikonin on breast cancer cells in vitro and in vivo

BMC Complementary Medicine and Therapies
Background Breast cancer seriously affects physical and mental health of women. Despite advances in the clinical use of different treatments, breast cancer remains a major cause of mortality.
Chuyi Yu, Haoyu Xing, Xiaguo Fu, Yingying Zhang, Xiufang Yan, Jianjia Feng, Zhouqin He, Li Ru, Chunlong Huang, Jianming Liang   +9 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Information security strategy in telemedicine and e-health systems: A case study of England’s shared electronic health record system

, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 9/11/2010.Shared electronic health record (EHR) systems constitute an important Telemedicine and e-Health application. Successful implementation of shared
Mohammad, Yara Mahmoud
core  

Assessing the Systemic Impact of Endometriosis on Chronic Pain, Mental Health, and Other Internal Medicine Conditions

Endometriosis is a chronic inflammatory condition predominantly affecting reproductive-aged women, characterized by ectopic endometrial tissue and significant symptom burden, including chronic pelvic pain, dysmenorrhea, and dyspareunia. While traditionally considered a gynecological disorder, emerging evidence highlights its systemic impact involving ...
Dr. Lamyaa Ahmed Abed, Dr. Rana Hadi Salloomi, Dr. Shaymaa Muhammad Mutar   +2 more
openaire   +2 more sources