Results 81 to 90 of about 3,865,257 (306)

Creating Safe Connections: A Co-Designed E-Learning Module to Advance Equity and Social Accountability in Preventative Primary Care

open access: yesAdvances in Medical Education and Practice
Ambreen Sayani,1,2 Zeenat Ladak,1,3 Jackie Manthorne,4 Erika Nicholson,5 Gary C Bloch,6,7 Janet Parsons,2 Stephen W Hwang,6 Bikila Amenu,8 Howard Freedman,8 Tara Jeji,8 Angus Pratt,8 Vinesha Ramasamy,8 Jean-Claude Camus,8 C Nadine Wathen,9 Jennifer CD ...
Sayani A   +16 more
doaj  

Asociación de divertículos periampulares con canulación difícil. Experiencia en centro hospitalario de segundo nivel

open access: yesEndoscopia
Introducción: La colangiopancreatografía retrógrada endoscópica (CPRE) presenta una prevalencia de divertículos duodenales (DD) de aproximadamente el 5-30%, asociándose a canulación difícil y complicaciones.
Guadalupe del C. Che-Cantun   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Traditional Chinese medicine phenomics research on glycolipid metabolism disorder: a review

open access: yesDigital Chinese Medicine
Traditional Chinese medicine (TCM) has demonstrated unique advantages in the prevention and treatment of chronic diseases such as glycolipid metabolism disorder.
Xinyi Fang   +6 more
doaj   +1 more source

Capturing Scientific Knowledge on Medical Risk Factors [PDF]

open access: yes, 2015
In this paper, we describe a model for representing scientific knowledge of risk factors in medicine in an explicit format which enables its use for automated reasoning. The resulting model supports linking the conclusions of up-to-date clinical research
Domingue, John   +5 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

External application of traditional Chinese medicine in combination with three-step analgesic ladder therapy for cancer-induced bone pain: a systematic review and meta-analysis

open access: yesDigital Chinese Medicine
Objective: To systematically evaluate the overall efficacy of external application of traditional Chinese medicine (EA-TCM) in combination with oral three-step analgesic ladder therapy for patients suffering from cancer-induced bone pain (CIBP). Methods:
Fei Wang   +6 more
doaj   +1 more source

Ontology as the core discipline of biomedical informatics: Legacies of the past and recommendations for the future direction of research [PDF]

open access: yes, 2007
The automatic integration of rapidly expanding information resources in the life sciences is one of the most challenging goals facing biomedical research today.
Ceusters, Werner, Smith, Barry
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

TCMLCM: an intelligent question-answering model for traditional Chinese medicine lung cancer based on the KG2TRAG method

open access: yesDigital Chinese Medicine
Objective: To improve the accuracy and professionalism of question-answering (QA) model in traditional Chinese medicine (TCM) lung cancer by integrating large language models with structured knowledge graphs using the knowledge graph (KG) to text ...
Zhou Chunfang   +4 more
doaj   +1 more source

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