Results 241 to 250 of about 3,865,257 (306)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Acceptable accuracy for medical AI: a survey of physicians and the general population in Sweden. [PDF]

BMJ Health Care Inform
Arvidsson R, Widén J, Al-Naasan L, Gunnarsson RKK, Nymberg P, Blease CR, Moberg A, Sundvall PD, Wikberg C, Sundemo D.   +9 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Regulatory and HTA framework for herbal medicines in Indonesia. [PDF]

J Pharm Policy Pract
Kashuri M, Ikrar T, Sauriasari R, Juwono V, Yanuar A.   +4 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Harnessing big data and artificial intelligence in transfusion medicine: Opportunities for precision, safety and efficiency. [PDF]

Vox Sang
Raza S, Goel R, Erikstrup C, D'Alessandro A, Custer B, Li N, ISBT BIG DATA Working Party.   +6 more
europepmc   +1 more source

Rural America Nears a Cliff: Federal Funding Cuts Threaten Health Systems and Anesthesia Care. [PDF]

Anesthesiology
Yan C, Singh NS, Sanghvi CD, Pritzlaff SG.   +3 more
europepmc   +1 more source

Trends and Types of Medical Errors Reporting Following the Implementation of Electronic Health Record System. [PDF]

Drug Healthc Patient Saf
A'aqoulah A, Alqahtani M, Bin Dayel DF, Zarbah B, Kalmey F, Shattat G, Abusaris R.   +6 more
europepmc   +1 more source

Digital vaccines for immunization equity: an approach to strengthen vaccine delivery and public trust in low- and middle-income countries. [PDF]

JAMIA Open
Othman ZK, Ahmed MM, Okesanya OJ, Musa SS, Lucero-Prisno DE.   +4 more
europepmc   +1 more source

Be AWARE: An Anti-bias Toolkit to Limit Bias in Narrative Evaluation of Medical Trainees. [PDF]

MedEdPORTAL
Sandgren K, Baranay M, Koestner B, Schmitz A.   +3 more
europepmc   +1 more source